SCHEMBL32687222

SCHEMBL32687222

Cn1ncc2cc(-c3ccc(C[C@H]4NC[C@H](O)[C@H]4OCc4ccccc4)cc3)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 2/20 0.42
▸ PDE1C Q14123 2/20 0.42
▸ AR P10275 2/20 0.40
▸ GRIN2B Q13224 1/20 0.39
▸ SIGMAR1 Q99720 3/20 0.38
▸ DRD4 P21917 3/20 0.38
▸ DRD3 P35462 1/20 0.38
▸ TMEM97 Q5BJF2 2/20 0.37
▸ CTSC P53634 1/20 0.36
▸ CYP2D6 P10635 3/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SLC2A1 P11166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687707 0.90 WNT1 (0.37) BCHESIGMAR1DRD4DRD3TMEM97
SCHEMBL32687049 0.90 BCHE (0.46) BCHEPDE1CARGRIN2BSIGMAR1
SCHEMBL32687201 0.89 SIGMAR1 (0.37) BCHEPDE1CARGRIN2BSIGMAR1
SCHEMBL32687536 0.89 CYP2D6 (0.39) GRIN2BSIGMAR1DRD4TMEM97CTSC
SCHEMBL32687195 0.86 CTSC (0.35) SIGMAR1DRD4TMEM97CTSCCYP2D6
SCHEMBL32687150 0.85 CYP2D6 (0.40) PDE1CARCTSCCYP2D6SMN1; SMN2
SCHEMBL32687373 0.84 CYP2D6 (0.39) PDE1CARCTSCCYP2D6SMN1; SMN2
SCHEMBL32687507 0.82 ERCC1 (0.40) PDE1CCTSCCYP2D6SMN1; SMN2LMNA
SCHEMBL32687035 0.77 CCNC (0.35) BCHECTSCFASN
SCHEMBL32686993 0.74 BCHE (0.47) BCHECYP2D6SMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 BCHE 4609/4885PDE1C 1403/4885AR 2892/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS BCHE 4667/4885PDE1C 4088/4885AR 1454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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