SCHEMBL32687131

SCHEMBL32687131

C=CC(F)(F)O[C@@H]1[C@@H](OC(=O)OC(C)(C)C)CN(C(=O)OC(C)(C)C)[C@@H]1Cc1ccc(-c2cncs2)cc1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.39
▸ HCRTR1 O43613 2/20 0.33
▸ HCRTR2 O43614 2/20 0.33
▸ WNT1 P04628 1/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ DYRK1A Q13627 1/20 0.32
▸ DPP4 P27487 1/20 0.31
▸ TACR1 P25103 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687718 0.88 GPR119 (0.41) GPR119HCRTR1HCRTR2DPP4
SCHEMBL31377330 0.86 GPR119 (0.42) GPR119HCRTR1HCRTR2WNT1GSK3B
SCHEMBL32687119 0.86 GPR119 (0.36) GPR119HCRTR1HCRTR2
SCHEMBL32687199 0.86 GPR119 (0.42) GPR119HCRTR1HCRTR2WNT1GSK3B
SCHEMBL32687791 0.85 HDAC1 (0.38) GPR119
SCHEMBL32687326 0.85 GPR119 (0.40) GPR119HCRTR1HCRTR2WNT1GSK3B
SCHEMBL31377329 0.84 GPR119 (0.44) GPR119HCRTR1HCRTR2WNT1GSK3B
SCHEMBL32687768 0.84 ALDH1A1 (0.34) DPP4TACR1
SCHEMBL32687070 0.83 GPR119 (0.40) GPR119HCRTR1HCRTR2WNT1GSK3B
SCHEMBL32687063 0.82 TACR1 (0.33) TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 GPR119 3997/4885HCRTR1 4584/4885HCRTR2 4397/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS GPR119 3752/4885HCRTR1 3614/4885HCRTR2 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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