SCHEMBL3268722

SCHEMBL3268722

COC(=O)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 2/20 0.51
PYGB P11216 2/20 0.50
GAA P10253 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 1/20 0.44
SNCA P37840 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
LGALS3 P17931 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15444965 1.00 LGALS8 (0.51) LGALS8PYGBGAAL3MBTL1MAPT
SCHEMBL8591368 1.00 LGALS8 (0.51) LGALS8PYGBGAAL3MBTL1MAPT
SCHEMBL8591360 1.00 LGALS8 (0.51) LGALS8PYGBGAAL3MBTL1MAPT
SCHEMBL14210604 1.00 LGALS8 (0.51) LGALS8PYGBGAAL3MBTL1MAPT
SCHEMBL8811814 0.86 IGF2R (0.44) LGALS8
SCHEMBL8811807 0.86 IGF2R (0.44) LGALS8
SCHEMBL12500139 0.84 LGALS8 (0.49) LGALS8PYGBGAALGALS3
SCHEMBL15316747 0.84 LGALS8 (0.49) LGALS8PYGBGAALGALS3
SCHEMBL17274485 0.81 GAA (0.51) LGALS8GAAL3MBTL1MAPTLGALS3
SCHEMBL1450206 0.81 GAA (0.51) LGALS8GAAL3MBTL1MAPTLGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1400550-B1 BRANCHED POLYALKYLENE GLYCOLS KYOWA HAKKO KIRIN CO LTD (JP) 2010-06-23 EP disclosed
US-7547765-B2 Branched polyalkylene glycols KYOWA HAKKO KIRIN CO., LTD. (JP) 2009-06-16 US disclosed
US-20080125350-A1 BRANCHED POLYALKYLENE GLYCOLS KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-05-29 US disclosed
US-7291713-B2 Branched polyalkylene glycols KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-11-06 US disclosed
US-20050063936-A1 Branched polyalkylene glycols KYOWA HAKKO KIRIN CO., LTD. (JP) 2005-03-24 US disclosed
EP-1400550-A1 BRANCHED POLYALKYLENE GLYCOLS Kyowa Hakko Kogyo Co., Ltd (JP) 2004-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125350-A1 BRANCHED POLYALKYLENE GLYCOLS LNPEP, ANPEP, ENPEP LGALS8 197/4885PYGB 639/4885GAA 628/4885
US-20050063936-A1 Branched polyalkylene glycols LNPEP, ANPEP, ENPEP LGALS8 197/4885PYGB 639/4885GAA 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.