Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.47 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688250 | 0.93 | HSD11B1 (0.41) | HSD11B1HSD11B2ACMSDPOLBMEN1 | |
| SCHEMBL32688115 | 0.90 | HPGD (0.41) | HSD11B1HSD11B2MEN1KMT2ACXCR2 | |
| SCHEMBL32688147 | 0.90 | HSD11B1 (0.40) | HSD11B1HSD11B2POLBMEN1KMT2A | |
| SCHEMBL32688008 | 0.90 | MEN1 (0.42) | HSD11B1HSD11B2ACMSDPOLBMEN1 | |
| SCHEMBL32688050 | 0.87 | HSD11B1 (0.44) | HSD11B1HSD11B2POLBCXCR2BRD4 | |
| SCHEMBL32688370 | 0.87 | POLB (0.41) | HSD11B1HSD11B2ACMSDPOLBMEN1 | |
| SCHEMBL32688269 | 0.81 | HSD11B1 (0.45) | HSD11B1ACMSDPOLBMEN1KMT2A | |
| SCHEMBL32688201 | 0.81 | HSD11B1 (0.36) | HSD11B1HSD11B2CXCR2PDE9A | |
| SCHEMBL32688166 | 0.81 | HSD11B1 (0.41) | HSD11B1HSD11B2MEN1KMT2APDE9A | |
| SCHEMBL32688034 | 0.80 | PDE9A (0.43) | POLBMEN1KMT2ACXCR2PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | HSD11B1 61/4885HSD11B2 131/4885ACMSD 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.