Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688008 | 0.89 | MEN1 (0.42) | HSD11B1HSD11B2CXCR2BRD4POLB | |
| SCHEMBL32688250 | 0.89 | HSD11B1 (0.41) | HSD11B1HSD11B2CXCR2PIM1KDM4E | |
| SCHEMBL32688028 | 0.87 | HSD11B1 (0.47) | HSD11B1HSD11B2CXCR2BRD4PIM1 | |
| SCHEMBL32688269 | 0.87 | HSD11B1 (0.45) | HSD11B1CXCR2PIM1KDM4EGLA | |
| SCHEMBL32688166 | 0.85 | HSD11B1 (0.41) | HSD11B1HSD11B2 | |
| SCHEMBL32688201 | 0.85 | HSD11B1 (0.36) | HSD11B1HSD11B2CXCR2 | |
| SCHEMBL32688133 | 0.84 | HSD11B1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL32688160 | 0.84 | HSD11B1 (0.36) | HSD11B1HSD11B2 | |
| SCHEMBL32688034 | 0.84 | PDE9A (0.43) | CXCR2KDM4EPOLB | |
| SCHEMBL32688115 | 0.83 | HPGD (0.41) | HSD11B1HSD11B2CXCR2BRD4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | HSD11B1 61/4885HSD11B2 131/4885CXCR2 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.