Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339404 | 0.79 | ATM (0.58) | KDM4ETDP1RECQLBIRC5PIM1 | |
| SCHEMBL32688042 | 0.76 | ACMSD (0.52) | KDM4ETDP1RECQLFOLH1ATM | |
| SCHEMBL32688076 | 0.74 | KDM4E (0.50) | KDM4ETDP1RECQLBIRC5PIM1 | |
| SCHEMBL1343584 | 0.72 | CYP3A4 (0.49) | KDM4EFOLH1CYP3A4CYP2C9ALOX12 | |
| SCHEMBL32687996 | 0.71 | KDM4E (0.43) | KDM4ETDP1RECQLBIRC5PIM1 | |
| Water SCHEMBL27395300 | 0.71 | ALDH1A1 (0.68) | KDM4EFOLH1CYP3A4CYP2C9ALOX12 | |
| SCHEMBL10697723 | 0.71 | CYP3A4 (0.47) | FOLH1CYP3A4CYP2C9ALOX12ALDH1A1 | |
| SCHEMBL20340080 | 0.70 | KDM4E (0.49) | KDM4ETDP1RECQLALDH1A1KMT2A | |
| SCHEMBL20339604 | 0.70 | KDM4E (0.51) | KDM4ETDP1RECQLBIRC5PIM1 | |
| SCHEMBL20350824 | 0.69 | KDM4E (0.50) | KDM4ETDP1RECQLPIM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | KDM4E 3207/4885TDP1 1571/4885RECQL 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.