Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.37 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688485 | 0.88 | KMT2A (0.33) | HSD11B1CUL4AKMT2AACMSDHPGD | |
| SCHEMBL32688001 | 0.87 | CUL4A (0.49) | HSD11B1CUL4AKMT2AACMSDHPGD | |
| SCHEMBL32688370 | 0.84 | POLB (0.41) | HSD11B1KMT2AACMSDHPGDMEN1 | |
| SCHEMBL32688365 | 0.83 | ALDH1A1 (0.44) | KMT2AACMSDHPGDMEN1ALDH1A1 | |
| SCHEMBL32688035 | 0.82 | MEN1 (0.41) | HSD11B1KMT2AACMSDMEN1POLB | |
| SCHEMBL32688298 | 0.81 | POLB (0.37) | HSD11B1KMT2AACMSDHPGDMEN1 | |
| SCHEMBL32688401 | 0.81 | POLB (0.37) | HSD11B1KMT2AACMSDHPGDMEN1 | |
| SCHEMBL32688318 | 0.80 | ALDH1A1 (0.40) | KMT2AMGLLHPGDMEN1ALDH1A1 | |
| SCHEMBL32688136 | 0.78 | HSD11B1 (0.41) | HSD11B1KMT2AACMSDMEN1ALDH1A1 | |
| SCHEMBL32688008 | 0.77 | MEN1 (0.42) | HSD11B1KMT2AACMSDHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | HSD11B1 61/4885CUL4A 2621/4885KMT2A 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.