Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688274 | 0.90 | BRD4 (0.38) | ALDH1A1TSHRHPGDHSD11B1KMT2A | |
| SCHEMBL32688472 | 0.84 | GRK6 (0.36) | ALDH1A1HPGDHSD11B1KMT2AKDM4E | |
| SCHEMBL32688199 | 0.84 | HSD11B1 (0.36) | ALDH1A1TSHRMAPTHPGDHSD11B1 | |
| SCHEMBL32688310 | 0.84 | GRK6 (0.37) | ALDH1A1HPGDHSD11B1KMT2AKDM4E | |
| SCHEMBL32688425 | 0.82 | KISS1R (0.39) | ALDH1A1 | |
| SCHEMBL32688262 | 0.81 | GRK6 (0.37) | HSD11B1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL32688163 | 0.81 | KISS1R (0.39) | TP53CYP3A4HTT | |
| SCHEMBL32687986 | 0.80 | KMT2A (0.39) | ALDH1A1HPGDHSD11B1KMT2AKDM4E | |
| SCHEMBL32688223 | 0.79 | KISS1R (0.35) | ALDH1A1TSHRMAPTHPGDHSD11B1 | |
| SCHEMBL32688048 | 0.77 | BRD4 (0.38) | ALDH1A1TSHRMAPTHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ALDH1A1 290/4885TSHR 983/4885MAPT 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.