Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971739 | 0.89 | HPGD (0.34) | P2RX7PTGS2ALDH1A1 | |
| SCHEMBL11350296 | 0.84 | P2RX7 (0.32) | P2RX7PTGS2 | |
| SCHEMBL8044926 | 0.84 | P2RX7 (0.32) | P2RX7PTGS2 | |
| SCHEMBL9594501 | 0.84 | P2RX7 (0.32) | P2RX7PTGS2 | |
| SCHEMBL6142427 | 0.79 | TDP1 (0.34) | ALDH1A1 | |
| SCHEMBL2476289 | 0.75 | GSK3B (0.32) | P2RX7ALDH1A1 | |
| SCHEMBL2476284 | 0.75 | GSK3B (0.32) | P2RX7ALDH1A1 | |
| SCHEMBL8112010 | 0.74 | KMT2A (0.33) | P2RX7ALDH1A1 | |
| SCHEMBL8112015 | 0.74 | KMT2A (0.33) | P2RX7ALDH1A1 | |
| SCHEMBL6015178 | 0.73 | PTGS2 (0.30) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201020-A2 | METHOD OF PRODUCING 2' -DEOXY-5-AZACYTIDINE (DECITABINE) | Cilag AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009047313-A2 | METHOD OF PRODUCING 2' -DEOXY-5-AZACYTIDINE (DECITABINE) | CILAG AG (CH) | 2009-04-16 | — | — | WO | disclosed |