Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 11/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22627874 | 1.00 | ATF4 (0.36) | ATF4KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL19555951 | 0.93 | ATF4 (0.45) | ATF4 | |
| SCHEMBL22956629 | 0.93 | ATF4 (0.38) | ATF4KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL19556229 | 0.93 | ATF4 (0.45) | ATF4 | |
| SCHEMBL22628024 | 0.92 | ATF4 (0.37) | ATF4KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL22628519 | 0.91 | ATF4 (0.47) | ATF4TSHRNPC1RAB9A | |
| SCHEMBL19556219 | 0.89 | ATF4 (0.37) | ATF4ALDH1A1HPGDTSHR | |
| SCHEMBL22627835 | 0.89 | L3MBTL1 (0.36) | KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL22437035 | 0.89 | ATF4 (0.37) | ATF4ALDH1A1HPGDTSHR | |
| SCHEMBL32689687 | 0.89 | L3MBTL1 (0.36) | KMT2AALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |