SCHEMBL32689780

SCHEMBL32689780

O=C(O)CNC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 1/20 0.36
▸ CAPN1 P07384 4/20 0.36
▸ ACE P12821 1/20 0.35
▸ TRHR P34981 1/20 0.34
▸ OPRM1 P35372 1/20 0.34
▸ OPRD1 P41143 1/20 0.34
▸ REN P00797 1/20 0.34
▸ CTSB P07858 1/20 0.34
▸ CMA1 P23946 1/20 0.34
▸ BDKRB2 P30411 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31406958 0.88 ACE (0.39) ACETRHRRENCMA1
SCHEMBL30558195 0.86 OPRM1 (0.43) OPRM1OPRD1REN
SCHEMBL29575853 0.85 TERT (0.42) TERTACEREN
SCHEMBL30445980 0.84 CAPN1 (0.41) CAPN1TRHROPRM1RENCTSB
SCHEMBL30452849 0.84 ACE (0.43) ACETRHRREN
SCHEMBL31518665 0.83 ACE (0.46) ACERENCMA1
SCHEMBL30829334 0.82 CTSC (0.51) ACETRHROPRM1RENCMA1
SCHEMBL29765258 0.81 CAPN1 (0.47) CAPN1ACERENCTSB
SCHEMBL29765105 0.81 CAPN1 (0.47) CAPN1ACERENCTSB
SCHEMBL29765249 0.81 CAPN1 (0.47) CAPN1ACERENCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4039710-B1 ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123 SANOFI SA (FR) 2026-03-25 — — EP disclosed
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