SCHEMBL32689790

SCHEMBL32689790

COc1ncc(Cl)cc1CCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.55
SLC13A5 Q86YT5 2/20 0.46
SLC13A2 Q13183 1/20 0.46
SLC13A3 Q8WWT9 1/20 0.46
POLB P06746 1/20 0.43
FFAR4 Q5NUL3 8/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
HDAC6 Q9UBN7 1/20 0.41
GPR17 Q13304 1/20 0.40
FFAR1 O14842 3/20 0.37
LMNA P02545 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689800 0.84 PLAU (0.51) PLAUSLC13A5FFAR4NPSR1L3MBTL1
SCHEMBL31717890 0.81 PLAU (0.51) PLAUFFAR4NPSR1GPR17
SCHEMBL32689803 0.80 PLAU (0.58) PLAUFFAR4NPSR1L3MBTL1GPR17
SCHEMBL32689806 0.79 PLAU (0.49) PLAUFFAR4GPR17FFAR1
SCHEMBL9672115 0.79 ALDH1A1 (0.41)
SCHEMBL12467412 0.79 CYP2C9 (0.43) SLC13A5SLC13A2SLC13A3FFAR4L3MBTL1
SCHEMBL5783160 0.77 CYP2C9 (0.42) PLAUSLC13A5SLC13A2SLC13A3POLB
SCHEMBL32689794 0.77 PLAU (0.44) PLAUPOLBFFAR4L3MBTL1GPR17
SCHEMBL28942777 0.77 LMNA (0.43) POLBFFAR4LMNA
SCHEMBL30364398 0.77 LMNA (0.43) POLBFFAR4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712969-A1 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2026-03-25 EP disclosed