SCHEMBL32689808

SCHEMBL32689808

Cc1nnc(-c2ccc(Cl)cc2CCC(=O)O)o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.49
TP53 P04637 2/20 0.49
FFAR1 O14842 3/20 0.42
FFAR4 Q5NUL3 2/20 0.42
TSHR P16473 4/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
HSD17B10 Q99714 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
S1PR1 P21453 1/20 0.41
MAPK14 Q16539 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
PPARG P37231 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689792 0.81 TP53 (0.46) SMN1; SMN2TP53FFAR1FFAR4ALDH1A1
SCHEMBL3746360 0.72 FFAR4 (0.66) FFAR1FFAR4RXRARXRB
SCHEMBL31276587 0.71 CTSL (0.43) SMN1; SMN2TP53TSHRHSD17B10MAPT
SCHEMBL31276831 0.70 MAPK14 (0.37) SMN1; SMN2TP53TSHRNPC1RAB9A
SCHEMBL31276643 0.70 NOTUM (0.47) SMN1; SMN2TP53TSHRNPC1RAB9A
SCHEMBL2236405 0.70 FFAR1 (0.40) SMN1; SMN2TP53FFAR1FFAR4TSHR
SCHEMBL5500307 0.70 SMN1; SMN2 (0.53) SMN1; SMN2TP53FFAR1FFAR4TSHR
SCHEMBL10745896 0.70 NPSR1 (0.63) FFAR1FFAR4POLBMAPTNPSR1
SCHEMBL17068804 0.69 SMN1; SMN2 (0.63) SMN1; SMN2TP53TSHRNPC1RAB9A
SCHEMBL32689799 0.69 FFAR1 (0.49) TP53FFAR1FFAR4TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712969-A1 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2026-03-25 EP disclosed