SCHEMBL32689792

SCHEMBL32689792

O=C(O)CCc1cc(Cl)ccc1-c1nnc(C2CC2)o1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALOX15B O15296 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TNKS O95271 8/20 0.40
PARP2 Q9UGN5 8/20 0.40
PARP1 P09874 7/20 0.40
ENPP2 Q13822 1/20 0.38
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689808 0.81 SMN1; SMN2 (0.49) TP53SMN1; SMN2ALDH1A1FFAR1FFAR4
SCHEMBL31276662 0.73 ALDH1A1 (0.51) TP53SMN1; SMN2ALOX15BALDH1A1
SCHEMBL31276907 0.72 SMN1; SMN2 (0.37) TP53SMN1; SMN2ALOX15BALDH1A1ENPP2
SCHEMBL31276396 0.70 CTSS (0.40) TP53SMN1; SMN2ALDH1A1
SCHEMBL3746360 0.69 FFAR4 (0.66) FFAR1FFAR4
SCHEMBL29988207 0.68 ALDH1A1 (0.66) SMN1; SMN2ALOX15BALDH1A1TNKSPARP2
SCHEMBL2236405 0.67 FFAR1 (0.40) TP53SMN1; SMN2FFAR1FFAR4
SCHEMBL5500307 0.66 SMN1; SMN2 (0.53) TP53SMN1; SMN2ALDH1A1FFAR1FFAR4
SCHEMBL17068804 0.66 SMN1; SMN2 (0.63) TP53SMN1; SMN2ALDH1A1
SCHEMBL29988217 0.66 ALDH1A1 (0.41) ALOX15BALDH1A1TNKSPARP2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712969-A1 CYCLIN INHIBITORS Circle Pharma, Inc. (US) 2026-03-25 EP disclosed