SCHEMBL32691458

SCHEMBL32691458

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.61
▸ C5AR1 P21730 2/20 0.55
▸ F2 P00734 5/20 0.52
▸ REN P00797 1/20 0.51
▸ OPRD1 P41143 2/20 0.50
▸ NTSR1 P30989 2/20 0.50
▸ OPRM1 P35372 1/20 0.50
▸ NTSR2 O95665 1/20 0.50
▸ SORT1 Q99523 1/20 0.50
▸ ANPEP P15144 1/20 0.50
▸ LNPEP Q9UIQ6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32691451 0.98 SLC6A2 (0.59) SLC6A2C5AR1F2RENOPRD1
SCHEMBL32691359 0.94 SLC6A2 (0.70) SLC6A2C5AR1F2RENOPRD1
SCHEMBL32691552 0.92 SLC6A2 (0.67) SLC6A2C5AR1F2RENOPRD1
SCHEMBL32691571 0.92 SLC6A2 (0.64) SLC6A2C5AR1RENOPRD1NTSR1
SCHEMBL32691265 0.90 SLC6A2 (0.62) SLC6A2C5AR1RENOPRD1NTSR1
SCHEMBL30558098 0.89 SLC6A2 (0.67) SLC6A2F2OPRD1NTSR1OPRM1
SCHEMBL8953877 0.86 C5AR1 (0.55) C5AR1F2REN
SCHEMBL29461549 0.86 F2 (0.60) SLC6A2F2RENOPRD1OPRM1
SCHEMBL10622567 0.86 C5AR1 (0.54) C5AR1F2REN
SCHEMBL8953791 0.86 C5AR1 (0.52) C5AR1F2REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085103-A1 LONG-ACTING INSULIN COMPOUND CHENGDU AODA BIOTECHNOLOGY CO LTD (CN) 2026-03-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085103-A1 LONG-ACTING INSULIN COMPOUND IAPP, INSR, IDE SLC6A2 2535/4885C5AR1 1779/4885F2 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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