SCHEMBL3269166

SCHEMBL3269166

Clc1ccc(Cl)c(-c2ccccc2)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.44
CYP1A2 P05177 2/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
MAPT P10636 1/20 0.42
ALDH1A1 P00352 1/20 0.40
TSHR P16473 2/20 0.38
FABP3 P05413 3/20 0.38
FABP4 P15090 3/20 0.38
FABP5 Q01469 1/20 0.38
TYMP P19971 1/20 0.38
ESR2 Q92731 1/20 0.37
MEN1 O00255 1/20 0.36
HSP90AA1 P07900 1/20 0.36
KMT2A Q03164 1/20 0.36
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
AHR P35869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368088 1.00 CYP2A6 (0.44) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL1696360 0.83 CYP2A6 (0.50) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL331204 0.81 ADORA2A (0.46) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL28656837 0.81 CYP2A6 (0.38) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL7106911 0.81 ESR2 (0.50) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL10584813 0.81 CYP2A6 (0.38) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL9162945 0.81 CYP2A6 (0.38) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL2936378 0.79 MEN1 (0.45) CYP2A6CYP1A2LMNAHTTMAPT
SCHEMBL30384693 0.79 AHR (0.48) CYP2A6CYP1A2LMNAMAPTALDH1A1
SCHEMBL4458291 0.79 AHR (0.48) CYP2A6CYP1A2LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-0968739-B1 Method for decomposing halogenated aliphatic and aromatic compounds CANON KK (JP) 2010-06-16 EP claimed
EP-1005881-B1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KK (JP) 2005-01-19 EP claimed
US-6616815-B2 Contacting under irradiation with light a medium containing at least one of a halogenated aliphatic hydrocarbon compound and an aromatic compound with functional water produced by electrolysis of water containing an electrolyte CANON KABUSHIKI KAISHA (JP) 2003-09-09 US claimed
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2003-09-04 US claimed
US-20020163135-A1 METHOD FOR DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS, METHOD FOR CLEANING MEDIUM CONTAMINATED WITH AT LEAST ONE OF THESE COMPOUNDS, AND APPARATUS FOR THESE CANON KABUSHIKI KAISHA (JP) 2002-11-07 US claimed
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2002-09-19 US claimed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
EP-0968739-B1 Method for decomposing halogenated aliphatic and aromatic compounds CANON KK (JP) 2010-06-16 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1005881-B1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KK (JP) 2005-01-19 EP disclosed
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2002-09-19 US disclosed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP disclosed
CN-1245080-A Process for decomposing halogen ester group hydrocarbon compound or aromatic compound and device thereof and process for purifying waste gas and device for this method CANON KK (JP) 2000-02-23 CN disclosed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP disclosed
WO-1998052648-A1 METHOD FOR DECHLORINATING POLYCHLORINATED BIPHENYLS AND GRANULES FOR USE IN METHOD MICHIGAN BIOTECHNOLOGY INSTITUTE (US) 1998-11-26 WO disclosed
US-5635393-A CULTURING ANAEROBIC METHANOGENIC DECHLORINATING MICROORGANISMS IN NUTRIENT SLUDGES UNTIL GRANULES FORM BHATNAGAR LAKSHMI (US) 1997-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds AHR, ARNT, TRPA1 CYP2A6 1561/4885CYP1A2 350/4885LMNA 3050/4885
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME AHR, ARNT, TRPA1 CYP2A6 1162/4885CYP1A2 213/4885LMNA 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.