Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446143 | 0.86 | ESR2 (0.48) | ESR2CYP3A4MAPK1HTTTSHR | |
| SCHEMBL27588764 | 0.84 | ESR2 (0.52) | ESR2CYP3A4MAPK1HTTALDH1A1 | |
| SCHEMBL6754088 | 0.83 | CYP3A4 (0.68) | ESR2CYP3A4MAPK1TSHRALDH1A1 | |
| SCHEMBL27505789 | 0.83 | ESR2 (0.50) | ESR2CYP3A4MAPK1HTTALDH1A1 | |
| SCHEMBL29368088 | 0.81 | CYP2A6 (0.44) | ESR2CYP3A4MAPK1HTTTSHR | |
| SCHEMBL3269166 | 0.81 | CYP2A6 (0.44) | ESR2CYP3A4MAPK1HTTTSHR | |
| SCHEMBL27728743 | 0.81 | ALOX5 (0.52) | ESR2CYP3A4HTTALDH1A1ALOX5 | |
| SCHEMBL28999631 | 0.81 | ESR2 (0.48) | ESR2CYP3A4MAPK1HTTALDH1A1 | |
| SCHEMBL22891656 | 0.79 | ESR2 (0.42) | ESR2CYP3A4MAPK1HTTALDH1A1 | |
| SCHEMBL27530617 | 0.79 | TTR (0.43) | ESR2CYP3A4HTTALOX5THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458993-B1 | AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS | VANTICO INC. | 2002-10-01 | — | — | US | claimed |
| US-20020055648-A1 | Cyanate esters having flame resistant properties | JPMORGAN CHASE BANK, N.A. | 2002-05-09 | — | — | US | claimed |
| US-4410737-A | Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | claimed |
| US-4410738-A | Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | claimed |
| US-4410739-A | LEWIS ACID, NOBLE METAL CATALYST | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | claimed |
| CN-100335559-C | High optical contrast resin composition and electronic package utilizing same | IBM (US) | 2007-09-05 | — | — | CN | disclosed |
| EP-1161414-B1 | CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES | VANTICO AG (CH) | 2003-10-01 | — | — | EP | disclosed |
| US-6458993-B1 | AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS | VANTICO INC. | 2002-10-01 | — | — | US | disclosed |
| US-20020055648-A1 | Cyanate esters having flame resistant properties | JPMORGAN CHASE BANK, N.A. | 2002-05-09 | — | — | US | disclosed |
| CN-1343199-A | Cyanate esters having flame resistant properties | VANTICO AG (CH) | 2002-04-03 | — | — | CN | disclosed |
| EP-1161414-A1 | CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES | Vantico AG (CH) | 2001-12-12 | — | — | EP | disclosed |
| EP-1145083-A2 | HYBRID SURFACE MODIFICATION PROCESS AND ARTICLE | BMC Industries, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-0369194-A2 | Sulfonium salts and use and preparation thereof | International Business Machines Corporation (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4540834-A | HYDRODECHLORINATION OF POLYCHLOROPHENOL, HYDRIOTIC ACID | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-09-10 | — | — | US | disclosed |
| US-4410738-A | Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | disclosed |
| US-4410737-A | Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | disclosed |
| US-4410739-A | LEWIS ACID, NOBLE METAL CATALYST | RHONE-POULENC INDUSTRIES (FR) | 1983-10-18 | — | — | US | disclosed |
| US-4410647-A | POLYANHYDRIDE, 2-ACETOXYTRIMETHYLENEBIS/ANHYDROTRIMELLITATE/ | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0053280-A1 | Sealing composition, method for preparing said composition, integrated circuit module sealed therewith, and process for sealing | International Business Machines Corporation (US) | 1982-06-09 | — | — | EP | disclosed |
| US-4292230-A | Screen-printing composition and use thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055648-A1 | Cyanate esters having flame resistant properties | PCCA, FABP4, MCCC2 | ESR2 3000/4885CYP3A4 464/4885MAPK1 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.