Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 13/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269697 | 0.78 | P2RX4 (0.39) | ALDH1A1P2RX4SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL47007 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL31067286 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| Hydrogen Sulfide SCHEMBL28845788 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL3268784 | 0.76 | P2RX4 (0.37) | ALDH1A1P2RX4SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL195171 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL2804853 | 0.71 | MAOA (0.62) | KDM4EALDH1A1MAPTNPSR1MAOA | |
| SCHEMBL12532095 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL4012288 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT | |
| Formic Acid SCHEMBL8502185 | 0.68 | P2RX4 (0.49) | KDM4EALDH1A1P2RX4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2115533-B1 | PHOTOCHROMIC H-ANNELLATED BENZO(F)CHROMENES | RODENSTOCK GMBH (DE) | 2010-06-30 | — | — | EP | claimed |
| EP-2115533-A1 | PHOTOCHROMIC H-ANNELLATED BENZOÝF¨CHROMENES | Rodenstock GmbH (DE) | 2009-11-11 | — | — | EP | claimed |
| WO-2008077634-A1 | PHOTOCHROMIC H-ANNELLATED BENZO[F]CHROMENES | RODENSTOCK GMBH (DE) | 2008-07-03 | — | — | WO | claimed |
| EP-2115533-B1 | PHOTOCHROMIC H-ANNELLATED BENZO(F)CHROMENES | RODENSTOCK GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| EP-2115533-A1 | PHOTOCHROMIC H-ANNELLATED BENZOÝF¨CHROMENES | Rodenstock GmbH (DE) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008077634-A1 | PHOTOCHROMIC H-ANNELLATED BENZO[F]CHROMENES | RODENSTOCK GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |