SCHEMBL3268784

SCHEMBL3268784

[c]1cccc2c1N(c1ccccc1)c1ccccc1O2

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 14/20 0.37
NPSR1 Q6W5P4 2/20 0.32
P2RX1 P51575 1/20 0.32
P2RX3 P56373 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CES2 O00748 1/20 0.32
BCHE P06276 1/20 0.32
GAA P10253 1/20 0.32
CES1 P23141 1/20 0.32
HPGD P15428 1/20 0.31
ALOX5 P09917 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406608 0.84 P2RX4 (0.47) P2RX4NPSR1P2RX1P2RX3ALDH1A1
SCHEMBL1573992 0.84 P2RX4 (0.47) P2RX4NPSR1P2RX1P2RX3ALDH1A1
SCHEMBL29379993 0.84 P2RX4 (0.47) P2RX4NPSR1P2RX1P2RX3ALDH1A1
SCHEMBL11311521 0.82 P2RX4 (0.46) P2RX4NPSR1P2RX1P2RX3ALDH1A1
SCHEMBL22964978 0.80 P2RX4 (0.44) P2RX4NPSR1P2RX1P2RX3ALDH1A1
SCHEMBL27688532 0.80 MGLL (0.37) P2RX4P2RX1GAA
SCHEMBL6123819 0.78 P2RX4 (0.47) P2RX4NPSR1P2RX1P2RX3MAPT
Thiophene SCHEMBL27789459 0.77 P2RX4 (0.40) P2RX4NPSR1P2RX1P2RX3ALDH1A1
SCHEMBL3269797 0.76 KDM4E (0.40) P2RX4NPSR1P2RX1MAPTSMN1; SMN2
Thiophene SCHEMBL28334340 0.76 P2RX4 (0.39) P2RX4NPSR1P2RX1P2RX3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2115533-B1 PHOTOCHROMIC H-ANNELLATED BENZO(F)CHROMENES RODENSTOCK GMBH (DE) 2010-06-30 EP claimed
EP-2115533-A1 PHOTOCHROMIC H-ANNELLATED BENZOÝF¨CHROMENES Rodenstock GmbH (DE) 2009-11-11 EP claimed
WO-2008077634-A1 PHOTOCHROMIC H-ANNELLATED BENZO[F]CHROMENES RODENSTOCK GMBH (DE) 2008-07-03 WO claimed
US-11939341-B2 Organic compound, electroluminescent material, and application thereof WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2024-03-26 US disclosed
CN-111808125-B Organic compound, organic electroluminescent material and application thereof 武汉天马微电子有限公司 2023-03-03 CN disclosed
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2021-05-20 US disclosed
CN-111808125-A Organic compound, organic electroluminescent material and application thereof 上海天马有机发光显示技术有限公司 2020-10-23 CN disclosed
EP-2115533-B1 PHOTOCHROMIC H-ANNELLATED BENZO(F)CHROMENES RODENSTOCK GMBH (DE) 2010-06-30 EP disclosed
EP-2115533-A1 PHOTOCHROMIC H-ANNELLATED BENZOÝF¨CHROMENES Rodenstock GmbH (DE) 2009-11-11 EP disclosed
WO-2008077634-A1 PHOTOCHROMIC H-ANNELLATED BENZO[F]CHROMENES RODENSTOCK GMBH (DE) 2008-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF ILK, OSTC, LEF1 P2RX4 1596/4885NPSR1 4470/4885P2RX1 1705/4885
US-11939341-B2 Organic compound, electroluminescent material, and application thereof ILK, OSTC, LEF1 P2RX4 1596/4885NPSR1 4470/4885P2RX1 1705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.