Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17258239 | 0.98 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL18764347 | 0.86 | THRB (0.43) | THRBMEN1KMT2ANOS1NOS2 | |
| SCHEMBL32905 | 0.80 | THRB (0.53) | THRBMEN1KMT2A | |
| SCHEMBL10506099 | 0.79 | — | — | |
| SCHEMBL17956901 | 0.78 | THRB (0.36) | THRBMEN1KMT2A | |
| SCHEMBL10703317 | 0.77 | — | — | |
| SCHEMBL11090052 | 0.77 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL39986 | 0.76 | — | — | |
| SCHEMBL10069416 | 0.76 | — | — | |
| SCHEMBL1987161 | 0.75 | NOS1 (0.39) | THRBNOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376438-A1 | METHOD FOR PRODUCING ISOCYANATES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-11 | — | — | US | claimed |
| EP-4543852-A1 | PRODUCING SPECIAL ISOCYANATES VIA CO-PHOSGENATION | Covestro Deutschland AG (DE) | 2025-04-30 | — | — | EP | claimed |
| CN-119365443-A | Process for producing isocyanates by phosgenation of mixtures of (aromatic) aliphatic diamines and cycloaliphatic diamines | 科思创德国股份有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119278196-A | Production of specific isocyanates by co-phosgenation | 科思创德国股份有限公司 | 2025-01-07 | — | — | CN | claimed |
| US-20240218205-A1 | CURABLE FILM-FORMING COMPOSITIONS AND COATED STRUCTURES WITH IMPROVED CORROSION RESISTANCE AND DURABILITY | PPG INDUSTRIES OHIO, INC. (US) | 2024-07-04 | — | — | US | claimed |
| US-11992811-B2 | Crosslinked hollow-fibre membranes and new process for manufacturing the same | EVONIK OPERATIONS GMBH (DE) | 2024-05-28 | — | — | US | claimed |
| EP-4347556-A1 | PROCESS FOR PREPARING AT LEAST ONE POLYISOCYANATE | BASF SE (DE) | 2024-04-10 | — | — | EP | claimed |
| CN-117659306-A | Dual-crosslinked acrylic acid secondary fraction, and preparation method and application thereof | 广东恒和永盛集团有限公司 | 2024-03-08 | — | — | CN | claimed |
| EP-4330306-A1 | CURABLE FILM-FORMING COMPOSITIONS AND COATED STRUCTURES WITH IMPROVED CORROSION RESISTANCE AND DURABILITY | PPG Industries Ohio, Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| CN-117500782-A | Process for preparing at least one polyisocyanate | 巴斯夫欧洲公司 | 2024-02-02 | — | — | CN | claimed |
| EP-1091929-A2 | SECONDARY ASPARTIC ACID AMIDE ESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-04-18 | — | — | EP | claimed |
| WO-2000001665-A2 | SECONDARY ASPARTIC ACID AMIDE ESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-01-13 | — | — | WO | claimed |
| US-5596030-A | Amide-containing self-emulsifying epoxy curing agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-01-21 | — | — | US | claimed |
| US-5576416-A | Amide-containing self-emulsifying epoxy curing agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1996-11-19 | — | — | US | claimed |
| US-5527839-A | BLEND CONTAINS A POLYAMINE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1996-06-18 | — | — | US | claimed |
| EP-0012931-B1 | COPOLYAMIDES BASED ON A MIXTURE OF CYCLOALIPHATIC AMINES AND MOULDED ARTICLES THEREOF | BAYER AG (DE) | 1983-09-14 | — | — | EP | claimed |
| EP-0003954-B1 | REACTIVE POLYOL COMPOSITIONS AND HIGH RESILIENCY POLYURETHANE FOAMS OBTAINED BY USING THESE COMPOSITIONS | BASF WYANDOTTE CORPORATION (US) | 1983-08-24 | — | — | EP | claimed |
| EP-0002431-B1 | TRANSPARENT POLYAMIDES AND THEIR USE FOR MAKING MOULDINGS | BAYER AG (DE) | 1981-03-25 | — | — | EP | claimed |
| US-4223127-A | Polyamides from 2,4'-diaminodicyclohexyl methane | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | claimed |
| EP-0003954-A1 | Reactive polyol compositions and high resiliency polyurethane foams obtained by using these compositions | BASF WYANDOTTE CORPORATION (US) | 1979-09-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376438-A1 | METHOD FOR PRODUCING ISOCYANATES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | APEH, CDIPT, DDT | THRB 4545/4885MEN1 1980/4885KMT2A 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.