Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | SORD | Q00796 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268994 | 0.89 | SIRT2 (0.46) | SIRT2SIRT1SIRT3HTR2CMALT1 | |
| SCHEMBL2757435 | 0.87 | DPP4 (0.44) | HTR2CMALT1HRH4DRD2DRD4 | |
| SCHEMBL238082 | 0.87 | SIRT2 (0.49) | SIRT2SIRT1SIRT3TPSAB1TPSD1 | |
| SCHEMBL3265661 | 0.85 | SIRT2 (0.49) | SIRT2SIRT1SIRT3DRD2DRD4 | |
| SCHEMBL3266253 | 0.83 | SIRT2 (0.48) | SIRT2SIRT1SIRT3HTR2CDRD2 | |
| SCHEMBL3269252 | 0.83 | DRD2 (0.50) | SIRT2SIRT1SIRT3HTR2CDRD2 | |
| SCHEMBL1728813 | 0.83 | SIRT2 (0.51) | SIRT2SIRT1SIRT3HTR2CMALT1 | |
| SCHEMBL3266163 | 0.83 | SIRT2 (0.44) | SIRT2SIRT1SIRT3MALT1TPSAB1 | |
| SCHEMBL241153 | 0.83 | DRD2 (0.45) | SIRT2SIRT1SIRT3HTR2CMALT1 | |
| SCHEMBL3265672 | 0.83 | CHRM4 (0.45) | SIRT2SIRT1SIRT3DRD2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004207-A1 | THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES | SANOFI-AVENTIS (FR) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004207-A1 | THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES | CLCN2, CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | SIRT2 268/4885SIRT1 987/4885SIRT3 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.