Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.48 |
| ▸ | SORD | Q00796 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727406 | 0.93 | HCAR2 (0.47) | SIRT2SIRT1SIRT3HCAR2HRH4 | |
| SCHEMBL1728699 | 0.88 | HRH4 (0.51) | HCAR2HRH4HTR2CSORDMALT1 | |
| SCHEMBL1727950 | 0.84 | SIRT2 (0.50) | SIRT2SIRT1SIRT3CHRM4 | |
| SCHEMBL1730265 | 0.84 | SIRT2 (0.50) | SIRT2SIRT1SIRT3CHRM4 | |
| SCHEMBL1727743 | 0.84 | SIRT2 (0.50) | SIRT2SIRT1SIRT3CHRM4MALT1 | |
| SCHEMBL3270079 | 0.83 | SIRT2 (0.49) | SIRT2SIRT1SIRT3HCAR2HRH4 | |
| SCHEMBL1728435 | 0.82 | SIRT2 (0.50) | SIRT2SIRT1SIRT3CHRM4ACHE | |
| SCHEMBL1729130 | 0.82 | ENPP1 (0.51) | SIRT2SIRT1SIRT3HTR2CCHRM4 | |
| SCHEMBL3268994 | 0.82 | SIRT2 (0.46) | SIRT2SIRT1SIRT3HCAR2HRH4 | |
| SCHEMBL240127 | 0.81 | SORD (0.57) | HCAR2HRH4HTR2CSORDMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |