Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.91 |
| ▸ | GLA | P06280 | 1/20 | 0.91 |
| ▸ | HPGD | P15428 | 1/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.91 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | CA1 | P00915 | 15/20 | 0.59 |
| ▸ | CA2 | P00918 | 15/20 | 0.59 |
| ▸ | CA9 | Q16790 | 13/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | CA3 | P07451 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA6 | P23280 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046781 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL11371614 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL11173505 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL11372853 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL10685394 | 1.00 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| Amylosulfuric Acid SCHEMBL1531835 | 0.98 | RECQL (0.87) | RECQLTSHRGLAHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL27563101 | 0.96 | RECQL (0.92) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL23387500 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390632 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390647 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651897-A1 | PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS | Syntis Bio, Inc. (US) | 2025-11-26 | — | — | EP | claimed |
| US-20240261411-A1 | PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS | SYNTIS BIO, INC. | 2024-08-08 | — | — | US | claimed |
| WO-2024155958-A1 | PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS | SYNTIS BIO, INC. (US) | 2024-07-25 | — | — | WO | claimed |
| US-20230225333-A1 | PEST CONTROL COMPOSITION | RECKITT BENCKISER LLC | 2023-07-20 | — | — | US | claimed |
| WO-2021255466-A1 | PEST CONTROL COMPOSITION | RECKITT BENCKISER LLC (US) | 2021-12-23 | — | — | WO | claimed |
| EP-0610026-B1 | Cosmetics with enhanced adherence to the skin | DOW CORNING (US) | 1997-06-18 | — | — | EP | claimed |
| US-5512272-A | AQUEOUS LATEX OF A CROSSLINKED POLYSILOXANE | DOW CORNING CORPORATION (US) | 1996-04-30 | — | — | US | claimed |
| US-5401515-A | Sustained release | DOW CORNING CORPORATION (US) | 1995-03-28 | — | — | US | claimed |
| US-5399342-A | Crosslinked polysiloxanes | DOW CORNING CORPORATION (US) | 1995-03-21 | — | — | US | claimed |
| US-5358990-A | Elastomeric films of crosslinked polysiloxane, colloidal silica and anionic surfactant | DOW CORNING CORPORATION (US) | 1994-10-25 | — | — | US | claimed |
| US-5310572-A | Polysiloxanes | DOW CORNING CORPORATION (US) | 1994-05-10 | — | — | US | claimed |
| EP-0202679-B1 | METHOD OF PRODUCING AQUEOUS LATEX OF CROSSLINKED POLYDIORGANOSILOXANE | DOW CORNING CORPORATION (US) | 1993-10-06 | — | — | EP | claimed |
| EP-0277740-B1 | AQUEOUS FILM-FORMING COMPOSITIONS FOR CONTROLLING THE RELEASE OF ACTIVE AGENTS AND PROCESS OF MAKING SAME | DOW CORNING CORPORATION (US) | 1993-05-19 | — | — | EP | claimed |
| EP-0166396-B1 | EMULSIONS OF CROSSLINKED POLYDIORGANOSILOXANES | DOW CORNING CORPORATION (US) | 1990-08-08 | — | — | EP | claimed |
| EP-0169386-B1 | POLYDIORGANOSILOXANE LATEX | DOW CORNING CORPORATION (US) | 1989-05-17 | — | — | EP | claimed |
| US-4568718-A | CROSSLINKING WITH AN ALKOXY SILICON COMPOUND AND ANIONIC SURFACTANT CATALYST; COATINGS | DOW CORNING CORPORATION (US) | 1986-02-04 | — | — | US | claimed |
| EP-0169386-A1 | Polydiorganosiloxane latex | DOW CORNING CORPORATION (US) | 1986-01-29 | — | — | EP | claimed |
| EP-0166396-A2 | Emulsions of crosslinked polydiorganosiloxanes | DOW CORNING CORPORATION (US) | 1986-01-02 | — | — | EP | claimed |
| US-4374953-A | Method for preparing polyacetals and polyketals by emulsion polymerization | DOW CORNING CORPORATION (US) | 1983-02-22 | — | — | US | claimed |
| US-4355154-A | Method for preparing condensation polymers by emulsion polymerization | DOW CORNING CORPORATION (US) | 1982-10-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240261411-A1 | PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS | FABP2, SLC10A2, FABP6 | RECQL 2765/4885TSHR 3261/4885GLA 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.