Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465365 | 0.88 | FAAH (0.65) | FAAHITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL8523026 | 0.88 | FAAH (0.65) | FAAHITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL20798175 | 0.84 | L3MBTL1 (0.52) | ACEGPR34MME | |
| SCHEMBL20798174 | 0.84 | L3MBTL1 (0.52) | ACEGPR34MME | |
| SCHEMBL15230995 | 0.84 | GLP1R (0.58) | FAAHITGB3ITGA2B | |
| SCHEMBL15231176 | 0.84 | GLP1R (0.58) | FAAHITGB3ITGA2B | |
| SCHEMBL15230991 | 0.84 | GLP1R (0.58) | FAAHITGB3ITGA2B | |
| SCHEMBL10825296 | 0.84 | PTPN1 (0.49) | FAAHSLC10A1 | |
| SCHEMBL11036712 | 0.83 | L3MBTL1 (0.51) | ACEGPR34MMECPA1 | |
| SCHEMBL9220945 | 0.82 | FAAH (0.65) | FAAHITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590931-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| CN-103080073-A | (2-Aryloxyacetylamino) phenyl-propionic acid derivatives, method for the production thereof and use thereof as medicaments | SANOFI SA | 2013-05-01 | — | — | CN | disclosed |
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |