Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | CPA2 | P48052 | 1/20 | 0.48 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798174 | 0.99 | L3MBTL1 (0.52) | L3MBTL1ACEGPR34FPR2PSMB5 | |
| SCHEMBL20798175 | 0.99 | L3MBTL1 (0.52) | L3MBTL1ACEGPR34FPR2PSMB5 | |
| SCHEMBL11049924 | 0.91 | ALDH1A1 (0.58) | — | |
| SCHEMBL20798186 | 0.88 | FOLH1 (0.52) | ACEGPR34MMECPA1CPA2 | |
| SCHEMBL20798185 | 0.88 | FOLH1 (0.52) | ACEGPR34MMECPA1CPA2 | |
| SCHEMBL5489495 | 0.86 | PSMB5 (0.62) | L3MBTL1ACEGPR34FPR2PSMB5 | |
| SCHEMBL2247123 | 0.86 | PSMB5 (0.62) | L3MBTL1ACEGPR34FPR2PSMB5 | |
| SCHEMBL9223275 | 0.85 | FAAH (0.57) | ACE | |
| SCHEMBL30737274 | 0.84 | GPR34 (0.47) | ACEGPR34FPR2MME | |
| SCHEMBL23201777 | 0.83 | PSMB5 (0.63) | L3MBTL1ACEFPR2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |