Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758299 | 0.82 | ASAH1 (0.60) | SMN1; SMN2ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL6569363 | 0.82 | LPAR5 (0.45) | SMN1; SMN2GPR88NPC1RAB9ALMNA | |
| SCHEMBL6570210 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2GPR88NPC1RAB9ALMNA | |
| SCHEMBL4127562 | 0.82 | POLB (0.53) | SMN1; SMN2POLBNPC1RAB9ALMNA | |
| SCHEMBL4127567 | 0.82 | POLB (0.53) | SMN1; SMN2POLBNPC1RAB9ALMNA | |
| SCHEMBL9829985 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL2249845 | 0.79 | TSHR (0.67) | SMN1; SMN2POLBLMNAITGB3ITGA2B | |
| SCHEMBL6857593 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBLMNAITGB3ITGA2B | |
| SCHEMBL6967716 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBITGB3ITGA2BALDH1A1 | |
| SCHEMBL9829245 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBLMNAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590931-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| CN-103080073-A | (2-Aryloxyacetylamino) phenyl-propionic acid derivatives, method for the production thereof and use thereof as medicaments | SANOFI SA | 2013-05-01 | — | — | CN | disclosed |
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |