Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.55 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.51 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758299 | 0.95 | ASAH1 (0.60) | SMN1; SMN2ITGB3ITGA2BALDH1A1ASAH1 | |
| SCHEMBL9829245 | 0.91 | SMN1; SMN2 (0.60) | SMN1; SMN2ITGB3ITGA2BALDH1A1ASAH1 | |
| SCHEMBL5700867 | 0.88 | ITGB3 (0.60) | SMN1; SMN2ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL5700862 | 0.88 | ITGB3 (0.60) | SMN1; SMN2ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL6857593 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2ITGB3ITGA2BALDH1A1ITGAV | |
| SCHEMBL7413120 | 0.83 | ASAH1 (0.60) | ALDH1A1ASAH1ACER2CERT1 | |
| SCHEMBL28217435 | 0.82 | ASAH1 (0.66) | SMN1; SMN2ALDH1A1ASAH1ACER2CERT1 | |
| SCHEMBL5720839 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1ASAH1ACER2 | |
| SCHEMBL327206 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ITGB3ITGA2BALDH1A1ASAH1 | |
| SCHEMBL9843976 | 0.81 | NPSR1 (0.77) | SMN1; SMN2NPSR1ALDH1A1ASAH1ACER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |