Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356820 | 0.90 | ANPEP (0.36) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL7816405 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1GRIN2DGRIN3BTHRB | |
| Ammonia Solution, Strong SCHEMBL786750 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TDP1GRIN2DGRIN3BTHRB | |
| Ammonia Solution, Strong SCHEMBL8010381 | 0.79 | FDPS (0.47) | ALDH1A1TDP1GRIN2DGRIN3BTHRB | |
| SCHEMBL4736414 | 0.77 | ANPEP (0.38) | ANPEPERAP2 | |
| Ammonia Solution, Strong SCHEMBL11336508 | 0.76 | FDPS (0.42) | ALDH1A1TDP1GRIN2DGRIN3BTHRB | |
| SCHEMBL10448870 | 0.73 | TYMS (0.58) | ALDH1A1TDP1GRIN2DGRIN3BTHRB | |
| SCHEMBL3277730 | 0.70 | FDPS (0.58) | ANPEPERAP2SIGMAR1 | |
| SCHEMBL9175624 | 0.70 | FDPS (0.58) | ANPEPERAP2SIGMAR1 | |
| SCHEMBL4447243 | 0.70 | FOLH1 (0.39) | GRIN2DGRIN3BTHRBGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7097823-B2 | High dose radionuclide complexes for bone marrow suppression | NEORX CORPORATION (US) | 2006-08-29 | — | — | US | claimed |
| US-20050238578-A1 | High dose radionuclide complexes for bone marrow suppression | NEORX CORPORATION | 2005-10-27 | — | — | US | claimed |
| US-20050063905-A1 | High dose radionuclide complexes for bone marrow suppression | NEORX CORPORATION | 2005-03-24 | — | — | US | claimed |
| US-6767531-B2 | RADIONUCLIDE COMPLEXED WITH A CHELATING AGENT SUCH AS MACROCYCLIC AMINOPHOSPHONIC ACID | NEORX CORPORATION | 2004-07-27 | — | — | US | claimed |
| US-20030118508-A1 | Treatment of osteomyelitis with radiopharmaceuticals | DOW GLOBAL TECHNOLOGIES INC. | 2003-06-26 | — | — | US | claimed |
| US-20020176818-A1 | High dose radionuclide complexes for bone marrow suppression | PONIARD PHARMACEUTICALS, INC. | 2002-11-28 | — | — | US | claimed |
| EP-1191948-A2 | HIGH DOSE RADIONUCLIDE COMPLEXES FOR BONE MARROW SUPPRESSION | NEORX CORPORATION (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2000076556-A9 | HIGH DOSE RADIONUCLIDE COMPLEXES FOR BONE MARROW SUPPRESSION | NEORX CORP (US) | 2001-11-08 | — | — | WO | claimed |
| WO-2000076556-A2 | HIGH DOSE RADIONUCLIDE COMPLEXES FOR BONE MARROW SUPPRESSION | NEORX CORPORATION (US) | 2000-12-21 | — | — | WO | claimed |
| EP-0462787-A1 | Radiopharmaceutical formulations, their method of administration and process of preparation | THE DOW CHEMICAL COMPANY (US) | 1991-12-27 | — | — | EP | claimed |
| US-5059412-A | Macrocyclic aminophosphonic acid complexes for the treatment of calcific tumors | THE DOW CHEMICAL COMPANY (US) | 1991-10-22 | — | — | US | claimed |
| US-4976950-A | ADMINISTERING COMPLEX OF YTTRIUM-90 AND 1,4,7,10-TETRAAZACYCLO DODECANE AMINOPHOSPHONIC ACID | THE DOW CHEMICAL COMPANY (US) | 1990-12-11 | — | — | US | claimed |
| EP-0374501-A1 | Bone marrow suppressing agents | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| US-4882142-A | ANTITUMOR | THE DOW CHEMICAL COMPANY (US) | 1989-11-21 | — | — | US | claimed |
| EP-4351652-A1 | DENDRIMER CONJUGATES AND METHODS OF USE THEREOF | Ashvattha Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| US-20230398241-A1 | RADIOLABELED ETHER DENDRIMER CONJUGATES FOR PET IMAGING AND RADIOTHERAPY | Ashvattha Therapeutics, Inc. (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230364244-A1 | DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO INJURED KIDNEY | Ashvattha Therapeutics, Inc. (US) | 2023-11-16 | — | — | US | disclosed |
| US-4976950-A | ADMINISTERING COMPLEX OF YTTRIUM-90 AND 1,4,7,10-TETRAAZACYCLO DODECANE AMINOPHOSPHONIC ACID | THE DOW CHEMICAL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4882142-A | ANTITUMOR | THE DOW CHEMICAL COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
| US-4882142-A | ANTITUMOR | THE DOW CHEMICAL COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230398241-A1 | RADIOLABELED ETHER DENDRIMER CONJUGATES FOR PET IMAGING AND RADIOTHERAPY | ESRRG, CD47, CD68 | ALDH1A1 3122/4885TDP1 1572/4885GRIN2D 851/4885 |
| US-20050238578-A1 | High dose radionuclide complexes for bone marrow suppression | CSF3R, ACP1, BPGM | ALDH1A1 4382/4885TDP1 3096/4885GRIN2D 4748/4885 |
| US-20020176818-A1 | High dose radionuclide complexes for bone marrow suppression | CSF3R, ACP1, BPGM | ALDH1A1 4382/4885TDP1 3096/4885GRIN2D 4748/4885 |
| US-20050063905-A1 | High dose radionuclide complexes for bone marrow suppression | CSF3R, ACP1, BPGM | ALDH1A1 4382/4885TDP1 3096/4885GRIN2D 4748/4885 |
| US-20230364244-A1 | DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO INJURED KIDNEY | PPARA, PPARD, PPARG | ALDH1A1 719/4885TDP1 4024/4885GRIN2D 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.