Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urethane SCHEMBL9356096 | 0.90 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11753538 | 0.84 | TSHR (0.45) | TSHR | |
| SCHEMBL8437710 | 0.83 | THRB (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8434847 | 0.83 | THRB (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9768558 | 0.83 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL8754872 | 0.82 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8435862 | 0.80 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22635790 | 0.80 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23494263 | 0.79 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL382201 | 0.79 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694298-B1 | PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME | SHOFU INC (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-5883153-A | SUSTAINED RELEASE GLASS IONOMERS | SHOFU INC. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0694298-A1 | PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME | SHOFU INC. (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5367002-A | Polyalkenoic acid, elutable glass filler | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0554890-A1 | Dental composition and method | DENTSPLY INTERNATIONAL, INC. (US) | 1993-08-11 | — | — | EP | disclosed |