Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437710 | 1.00 | THRB (0.41) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8435862 | 0.87 | TSHR (0.38) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL29738222 | 0.84 | CHRNB2 (0.42) | TSHRTDP1CHRNB2CHRNB4CHRNA3 | |
| Urethane SCHEMBL9356096 | 0.84 | TSHR (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL3272797 | 0.83 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL30827212 | 0.82 | TSHR (0.41) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL7061571 | 0.74 | TSHR (0.69) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9568827 | 0.74 | THRB (0.70) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8754872 | 0.72 | TSHR (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL14706828 | 0.72 | THRB (0.68) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001896-A | (A) TETRAHYDROFURFURYL METHACRYLATE; (B) ONE OR MORE MULTI-FUNCTIONAL METHACRYLATES, CONTAINING AT LEAST TWO METHACRYLOYL GROUPS; AND (C) A PHOTOPOLYMERIZATION INITIATOR IN SPECIFIC PARTS BY WEIGHT; ADHESIVE STRENGTH, AESTHETICS | GC CORPORATION (JP) | 1999-12-14 | — | — | US | disclosed |