Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434847 | 0.87 | THRB (0.41) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8437710 | 0.87 | THRB (0.41) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29738222 | 0.82 | CHRNB2 (0.42) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Urethane SCHEMBL9356096 | 0.81 | TSHR (0.44) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3272797 | 0.80 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL4640880 | 0.80 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL30827212 | 0.79 | TSHR (0.41) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1898441 | 0.78 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| 1,6-Hexanediol SCHEMBL14343519 | 0.77 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3503120 | 0.76 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001896-A | (A) TETRAHYDROFURFURYL METHACRYLATE; (B) ONE OR MORE MULTI-FUNCTIONAL METHACRYLATES, CONTAINING AT LEAST TWO METHACRYLOYL GROUPS; AND (C) A PHOTOPOLYMERIZATION INITIATOR IN SPECIFIC PARTS BY WEIGHT; ADHESIVE STRENGTH, AESTHETICS | GC CORPORATION (JP) | 1999-12-14 | — | — | US | disclosed |