Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728863 | 0.93 | LOXL2 (0.53) | LOXL2HRH3MTNR1AMTNR1BBCHE | |
| Formamide SCHEMBL6475057 | 0.91 | LOXL2 (0.51) | LOXL2HRH3MTNR1AMTNR1BBCHE | |
| SCHEMBL2970418 | 0.89 | LOXL2 (0.60) | LOXL2HRH3MTNR1AMTNR1BCHRNA7 | |
| SCHEMBL30539520 | 0.89 | LOXL2 (0.60) | LOXL2HRH3MTNR1AMTNR1BCHRNA7 | |
| SCHEMBL6860219 | 0.88 | LOXL2 (0.64) | LOXL2HRH3MTNR1AMTNR1BBCHE | |
| Biphenyl SCHEMBL29156860 | 0.87 | LOXL2 (0.47) | LOXL2HRH3MTNR1AMTNR1BBCHE | |
| SCHEMBL7169246 | 0.84 | LOXL2 (0.69) | LOXL2HRH3MTNR1AMTNR1BCHRNA7 | |
| SCHEMBL31059889 | 0.84 | LOXL2 (0.69) | LOXL2HRH3MTNR1AMTNR1BCHRNA7 | |
| SCHEMBL28335219 | 0.82 | LOXL2 (0.67) | LOXL2HRH3MTNR1AMTNR1BCHRNA7 | |
| SCHEMBL1713962 | 0.81 | LOXL2 (0.67) | LOXL2HRH3MTNR1AMTNR1BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194985-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | Medicines for Malaria Venture (CH) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009048957-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE (CH) | 2009-04-16 | — | — | WO | disclosed |