SCHEMBL3273375

SCHEMBL3273375

CC(=O)NC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13435533 0.73 ALDH1A1 (0.36)
SCHEMBL11812828 0.72 CA2 (0.35)
SCHEMBL2828712 0.71 ALDH1A1 (0.36)
SCHEMBL24369512 0.69
Trifluoroacetic Acid SCHEMBL30076041 0.69 EPHX1 (0.43)
SCHEMBL2909125 0.69 ALDH1A1 (0.31)
SCHEMBL6363154 0.69
SCHEMBL124179 0.69
SCHEMBL27265453 0.69 EPHX1 (0.42)
SCHEMBL971096 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120048989-A Fluorinated eutectic gel electrolyte for lithium battery and preparation method thereof 南开大学 2025-05-27 CN claimed
CN-105001031-A Ionic Iron (III) complex containing monophenol functionalized imidazoline cation and preparation method and application thereof UNIV SOOCHOW 2015-10-28 CN claimed
US-20100087496-A1 NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS NEUROSEARCH A/S (DK) 2010-04-08 US claimed
EP-2121569-A2 NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS NEUROSEARCH A/S (DK) 2009-11-25 EP claimed
WO-2008074755-A2 NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS NEUROSEARCH A/S (DK) 2008-06-26 WO claimed
EP-1044197-B1 PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKYNE CARBOXAMIDES AS CYTOSTATIC AGENTS AND IMMUNOSUPPRESSANTS ASTELLAS PHARMA GMBH (DE) 2006-04-19 EP claimed
EP-0392317-B1 Benzimidazoles, drugs containing these compounds and process for their preparation THOMAE GMBH DR K (DE) 1996-01-03 EP claimed
EP-0036116-B1 METHOD OF PREPARING AZO DYESTUFFS BAYER AG (DE) 1983-05-18 EP claimed
EP-4700124-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION Alnylam Pharmaceuticals, Inc. (US) 2026-02-25 EP disclosed
CN-120048989-A Fluorinated eutectic gel electrolyte for lithium battery and preparation method thereof 南开大学 2025-05-27 CN disclosed
US-20250092468-A1 BIOMARKERS OF RESPONSE TO HIF-2-ALPHA INHIBITION IN CANCER AND METHODS FOR THE USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-03-20 US disclosed
US-20250075208-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2025-03-06 US disclosed
US-12234516-B2 Biomarkers of response to HIF-2-alpha inhibition in cancer and methods for the use thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-25 US disclosed
US-12173288-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2024-12-24 US disclosed
CN-1133173-A Preparation of diuretic by using neuropsychic tension antagonist SANOFI SA (FR) 1996-10-16 CN disclosed
CN-1128030-A Heterocyclic amines having central nervous system activity UPJOHN CO (US) 1996-07-31 CN disclosed
CN-1120042-A Substituted 1-(7-chloroquinolin-4-yl)pyrazole-3-carboxamide N-oxide derivatives, method of preparing them and the pharmaceutical compositions in which they are present SANOFI SA (FR) 1996-04-10 CN disclosed
WO-1995029907-A1 BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-11-09 WO disclosed
EP-0641331-A1 CHIRAL INTERMEDIATES FOR THE PREPARATION OF ANTIDIABETICS THIAZOLES PFIZER INC. (US) 1995-03-08 EP disclosed
WO-1993002061-A1 CHIRAL INTERMEDIATES FOR THE PREPARATION OF ANTIDIABETICS THIAZOLES PFIZER, INC. (US) 1993-02-04 WO disclosed