Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL60557 | 0.96 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL60006 | 0.96 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAMAPTNOTUM | |
| Hydrochloric Acid SCHEMBL7520467 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRLMNAMAPTNOTUM | |
| Hydrochloric Acid SCHEMBL7520469 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRLMNAMAPTNOTUM | |
| Bromide SCHEMBL31571910 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRLMNAMAPTHTT | |
| SCHEMBL10801908 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNAMAPTTDP1 | |
| SCHEMBL47554 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNAMAPTTDP1 | |
| SCHEMBL2058664 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAMAPTTDP1 | |
| Fluoride Ion SCHEMBL10437963 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAMAPTTDP1 | |
| SCHEMBL12762137 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8852844-B2 | Composition for forming silicon-containing film, silicon-containing film-formed substrate and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20100086870-A1 | Composition for forming silicon-containing film, silicon-containing film-formed substrate and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-04-08 | — | — | US | disclosed |