Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274274 | 1.00 | SIGMAR1 (0.50) | SIGMAR1TACR1DRD4BCHEACHE | |
| Hydrochloric Acid SCHEMBL3273936 | 0.99 | SIGMAR1 (0.49) | SIGMAR1TACR1DRD4BCHEACHE | |
| Hydrochloric Acid SCHEMBL3273940 | 0.99 | SIGMAR1 (0.49) | SIGMAR1TACR1DRD4BCHEACHE | |
| Hydrochloric Acid SCHEMBL3273749 | 0.91 | SIGMAR1 (0.45) | SIGMAR1TACR1ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3273751 | 0.91 | SIGMAR1 (0.45) | SIGMAR1TACR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3273813 | 0.87 | DRD2 (0.38) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3273816 | 0.87 | DRD2 (0.38) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL3273550 | 0.85 | DRD1 (0.37) | SIGMAR1DRD4DRD2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3273557 | 0.85 | DRD1 (0.37) | SIGMAR1DRD4DRD2CYP1A2CYP3A4 | |
| SCHEMBL7221791 | 0.81 | PRCP (0.47) | DRD2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273883-B2 | Method for producing optically active 2-arylpiperazine derivative | KANEKA CORPORATION (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20100087643-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE | KANEKA CORPORATION (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-2119709-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE | Kaneka Corporation (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087643-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE | CYP2W1, AGPS, DHPS | SIGMAR1 1692/4885TACR1 1917/4885DRD4 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.