Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 20/20 | 0.84 |
| ▸ | FLT4 | P35916 | 20/20 | 0.84 |
| ▸ | KDR | P35968 | 20/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491628 | 0.85 | FLT1 (1.00) | FLT1FLT4KDR | |
| SCHEMBL31060564 | 0.85 | FLT1 (1.00) | FLT1FLT4KDR | |
| SCHEMBL5959031 | 0.83 | FLT1 (0.84) | FLT1FLT4KDR | |
| SCHEMBL4477897 | 0.82 | FLT1 (0.67) | FLT1FLT4KDR | |
| SCHEMBL4196234 | 0.82 | KDM4E (0.68) | FLT1FLT4KDRL3MBTL1 | |
| SCHEMBL3324399 | 0.79 | FLT1 (0.68) | FLT1FLT4KDR | |
| SCHEMBL31310442 | 0.77 | FLT1 (0.83) | FLT1FLT4KDR | |
| SCHEMBL1581237 | 0.76 | FLT1 (1.00) | FLT1FLT4KDR | |
| SCHEMBL3327224 | 0.76 | TMPRSS4 (0.65) | FLT1FLT4KDR | |
| SCHEMBL5959023 | 0.76 | FLT1 (1.00) | FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-08 | — | — | US | disclosed |
| EP-2121569-A2 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008074755-A2 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | TRPV1, TRPA1, TRPM8 | FLT1 4171/4885FLT4 3811/4885KDR 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.