Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 10/20 | 0.67 |
| ▸ | FLT4 | P35916 | 10/20 | 0.67 |
| ▸ | KDR | P35968 | 10/20 | 0.67 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.54 |
| ▸ | FBP1 | P09467 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196234 | 0.84 | KDM4E (0.68) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL3274474 | 0.82 | FLT1 (0.84) | FLT1FLT4KDR | |
| SCHEMBL4476657 | 0.81 | HPGD (0.55) | FLT1FLT4KDRKAT6AKDM4E | |
| SCHEMBL4472284 | 0.80 | KAT6A (0.58) | FLT1FLT4KDRKAT6AKDM4E | |
| SCHEMBL5959055 | 0.80 | FLT1 (1.00) | FLT1FLT4KDR | |
| SCHEMBL5958956 | 0.78 | FLT1 (0.77) | FLT1FLT4KDR | |
| SCHEMBL5959099 | 0.76 | FLT1 (0.81) | FLT1FLT4KDR | |
| SCHEMBL4457676 | 0.75 | EGFR (0.59) | FLT1FLT4KDRKAT6AKDM4E | |
| SCHEMBL2294952 | 0.75 | ALDH1A1 (0.48) | KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL22097470 | 0.75 | FLT1 (0.62) | FLT1FLT4KDRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |