Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.95 |
| ▸ | NSD2 | O96028 | 3/20 | 0.95 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.95 |
| ▸ | ABL1 | P00519 | 1/20 | 0.95 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.95 |
| ▸ | CES1 | P23141 | 1/20 | 0.95 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.95 |
| ▸ | GAA | P10253 | 1/20 | 0.86 |
| ▸ | PTPRC | P08575 | 2/20 | 0.75 |
| ▸ | CTSL | P07711 | 1/20 | 0.75 |
| ▸ | CTSS | P25774 | 1/20 | 0.75 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | S100A4 | P26447 | 6/20 | 0.63 |
| ▸ | CDC25B | P30305 | 3/20 | 0.63 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696693 | 1.00 | TDP2 (0.95) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL29419580 | 0.97 | TDP2 (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL460433 | 0.97 | TDP2 (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL4236482 | 0.95 | TDP2 (0.95) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL27145668 | 0.95 | TDP2 (0.95) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL579998 | 0.92 | GAA (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL29551149 | 0.92 | GAA (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL30774319 | 0.92 | GAA (1.00) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL5915065 | 0.87 | TDP2 (0.81) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL30385090 | 0.87 | TDP2 (0.79) | TDP2NSD2PAX8ABL1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100084268-A1 | LOW VOLUME ELECTROCHEMICAL BIOSENSOR | ABBOTT DIABETES CARE INC. | 2010-04-08 | — | — | US | disclosed |
| US-20080230384-A1 | LOW VOLUME ELECTROCHEMICAL BIOSENSOR | ABBOTT LABORATORIES (US) | 2008-09-25 | — | — | US | disclosed |
| US-20050067277-A1 | LOW VOLUME ELECTROCHEMICAL BIOSENSOR | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |