Sugi Predict

Sugi Predict / Compounds / SCHEMBL579998

SCHEMBL579998

SCHEMBL579998

O=C1c2cccnc2-c2ncccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 1.00
▸ TDP2 O95551 3/20 0.90
▸ NSD2 O96028 3/20 0.90
▸ PAX8 Q06710 3/20 0.90
▸ ABL1 P00519 1/20 0.90
▸ PLCG1 P19174 1/20 0.90
▸ CES1 P23141 1/20 0.90
▸ RIN1 Q13671 1/20 0.90
▸ TDP1 Q9NUW8 2/20 0.73
▸ MEN1 O00255 1/20 0.73
▸ THRB P10828 1/20 0.73
▸ BLM P54132 1/20 0.73
▸ KMT2A Q03164 1/20 0.73
▸ PTPRC P08575 2/20 0.71
▸ CTSL P07711 1/20 0.71
▸ CTSS P25774 1/20 0.71
▸ PTPN13 Q12923 1/20 0.71
▸ S100A4 P26447 6/20 0.65
▸ CDC25B P30305 3/20 0.65
▸ PADI1 Q9ULC6 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774319 1.00 GAA (1.00) GAATDP2NSD2PAX8ABL1
SCHEMBL29551149 1.00 GAA (1.00) GAATDP2NSD2PAX8ABL1
SCHEMBL460433 0.95 TDP2 (1.00) GAATDP2NSD2PAX8ABL1
SCHEMBL29419580 0.95 TDP2 (1.00) GAATDP2NSD2PAX8ABL1
SCHEMBL27145668 0.92 TDP2 (0.95) GAATDP2NSD2PAX8ABL1
SCHEMBL5696693 0.92 TDP2 (0.95) GAATDP2NSD2PAX8ABL1
SCHEMBL4236482 0.92 TDP2 (0.95) GAATDP2NSD2PAX8ABL1
SCHEMBL3275080 0.92 TDP2 (0.95) GAATDP2NSD2PAX8ABL1
SCHEMBL5915061 0.92 GAA (0.86) GAATDP2NSD2PAX8ABL1
SCHEMBL5915065 0.90 TDP2 (0.81) GAATDP2NSD2PAX8ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217208-A1 CHEMICAL MECHANICAL PLANARIZATION POLISHING FOR INTERCONNECTS DIFFUSION BARRIER MATERIALS VERSUM MATERIALS US, LLC (US) 2025-10-16 — — WO claimed
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 — — US claimed
CN-116158489-B Method for producing biological fermentation feed by using saccharomyces cerevisiae 内蒙古海邻科技发展有限公司 2023-07-18 — — CN claimed
CN-115246831-B Hg system 2+ Sensitive hydrazone derivative and preparation and application thereof 陕西学前师范学院 2023-07-07 — — CN claimed
CN-116284086-A Trans-borohydride method for biaryl internal alkyne compound 赣南医学院 2023-06-23 — — CN claimed
CN-116158489-A Method for producing biological fermentation feed by using saccharomyces cerevisiae 内蒙古海邻科技发展有限公司 2023-05-26 — — CN claimed
CN-111646889-B Green synthesis method of drug active molecules GC-24 and furaldehyde 兰州大学 2023-01-31 — — CN claimed
CN-115246831-A Hg 2+ Sensitive hydrazone derivatives, preparation and application thereof 陕西学前师范学院 2022-10-28 — — CN claimed
CN-111804287-B Fluorenone type chelate resin and preparation method and application thereof 兰州大学 2022-04-08 — — CN claimed
CN-110975924-B Catalyst for preparing cyclohexanone by catalytic oxidation of cyclohexene, preparation method and application thereof 上海应用技术大学 2021-12-07 — — CN claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 — — US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 — — EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 — — WO claimed
US-5439794-A Spectroscopically or photoactively determination when bound to Dna THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-08-08 — — US claimed
WO-1995007280-A1 DISUBSTITUTED POLYCYCLIC SYSTEMS AND PREPARATIVE METHODS THEREFOR THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-03-16 — — WO claimed
US-5272269-A Disubstituted polycyclic systems and preparative methods therefor THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-12-21 — — US claimed
US-5185447-A Treating polycyclic nitro compounds with aqueous base; cognition activators DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-02-09 — — US claimed
US-5157032-A Spectroscopically or photoactively determinable THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1992-10-20 — — US claimed
US-5112974-A Targets tumor cells for radiation treatment, metal complexes with amines or imines THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1992-05-12 — — US claimed
WO-1990005732-A1 MIXED LIGAND COMPLEXES AND USES THEREOF AS BINDING AGENTS AND PROBRES TO DNA THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) 1990-05-31 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst PPOX, TST, COX6C GAA 2862/4885TDP2 1563/4885NSD2 4030/4885
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 GAA 1882/4885TDP2 4007/4885NSD2 3853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.