SCHEMBL460433

SCHEMBL460433

O=C1C(=O)c2cccnc2-c2ncccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 3/20 1.00
NSD2 O96028 3/20 1.00
PAX8 Q06710 3/20 1.00
ABL1 P00519 1/20 1.00
PLCG1 P19174 1/20 1.00
CES1 P23141 1/20 1.00
RIN1 Q13671 1/20 1.00
GAA P10253 1/20 0.90
PTPRC P08575 2/20 0.78
CTSL P07711 1/20 0.78
CTSS P25774 1/20 0.78
PTPN13 Q12923 1/20 0.78
MEN1 O00255 1/20 0.73
THRB P10828 1/20 0.73
BLM P54132 1/20 0.73
KMT2A Q03164 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
S100A4 P26447 6/20 0.65
CDC25B P30305 3/20 0.65
PADI1 Q9ULC6 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419580 1.00 TDP2 (1.00) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL4236482 0.97 TDP2 (0.95) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL3275080 0.97 TDP2 (0.95) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL27145668 0.97 TDP2 (0.95) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL5696693 0.97 TDP2 (0.95) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL579998 0.95 GAA (1.00) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL30774319 0.95 GAA (1.00) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL29551149 0.95 GAA (1.00) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL5915065 0.90 TDP2 (0.81) TDP2NSD2PAX8ABL1PLCG1
SCHEMBL30385090 0.89 TDP2 (0.79) TDP2NSD2PAX8ABL1PLCG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629667-B2 Di-nitrogen ligands for supported coordinated platinum hydrosilylation catalysts THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-05-19 US claimed
US-12628491-B2 Organic-inorganic adhesion layer and its use in perovskite solar cells and modules Tandem PV (US) 2026-05-12 US claimed
US-20250374922-A1 METHOD FOR PREPARING ANTIBACTERIAL PBAT FOAMED MATERIAL FUJIAN KAIJI POLYMER MAT CO LTD (CN) 2025-12-11 US claimed
WO-2025043152-A1 METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-27 WO claimed
US-20240413352-A1 ENZYME ELECTRODE HAVING AN INTEGRATED RESERVOIR UNIVERSITE GRENOBLE ALPES (FR) 2024-12-12 US claimed
US-20240398294-A1 Disposable electrochemical biosensor based on NAD(P)-dependent dehydrogenase and diaphorase GLAS TRUST COMPANY LLC 2024-12-05 US claimed
US-20240334824-A1 Receptor material, synthesis method and use thereof SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-10-03 US claimed
EP-4416776-A2 ENZYME ELECTRODE HAVING AN INTEGRATED RESERVOIR Centre National de la Recherche Scientifique (FR) 2024-08-21 EP claimed
US-12064243-B2 Disposable electrochemical biosensor based on NAD(P)-dependent dehydrogenase and diaphorase NOVA BIOMEDICAL CORPORATION (US) 2024-08-20 US claimed
CN-118344406-A Lysosome-targeted ruthenium complex and preparation and application thereof 温州医科大学慈溪生物医药研究院 2024-07-16 CN claimed
WO-2004051774-A2 ENZYME IMMOBILIZATION FOR USE IN BIOFUEL CELLS AND SENSORS ST. LOUIS UNIVERSITY (US) 2004-06-17 WO claimed
US-20040101741-A1 Enzyme immobilization for use in biofuel cells and sensors ST. LOUIS UNIVERSITY 2004-05-27 US claimed
WO-2004038401-A2 BIOSENSOR HAVING HEMATOCRIT AND OXYGEN BIASES ABBOTT LABORATORIES (US) 2004-05-06 WO claimed
US-20040079653-A1 Biosensor having improved hematocrit and oxygen biases ABBOTT DIABETES CARE INC. 2004-04-29 US claimed
US-6720420-B2 AROMATIC, HETEROAROMATIC, OR ALIPHATIC SUBSTITUENTS AT THE 2 POSITION OF THE OXAZINE MOIETY; REACTING 3,3-DISUBSTITUTED ACRYLIC ACID, AZIDE SOURCE, QUINONE WITH CATALYTIC TRIPHENYLARSENIC OXIDE AND DBU; QUICKLY FADING GRAY COLOR JOHNSON & JOHNSON VISION CARE, INC. 2004-04-13 US claimed
WO-2003057679-A9 PHOTOCHROMIC OXAZINE COMPOUNDS AND METHODS FOR THEIR MANUFACTURE JOHNSON & JOHNSON VISION CARE (US) 2004-02-26 WO claimed
US-20030149032-A1 Photochromic oxazine compounds and methods for their manufacture ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2003-08-07 US claimed
WO-2003057679-A1 PHOTOCHROMIC OXAZINE COMPOUNDS AND METHODS FOR THEIR MANUFACTURE JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-07-17 WO claimed
WO-2003042195-A2 PHOTOCHROMIC OXAZINE COMPOUNDS AND METHODS FOR THEIR MANUFACTURE JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-05-22 WO claimed
WO-2002102861-A2 PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES ENI S.P.A. (IT) 2002-12-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149032-A1 Photochromic oxazine compounds and methods for their manufacture PPOX, TYR, DHPS TDP2 978/4885NSD2 1793/4885PAX8 733/4885
US-12629667-B2 Di-nitrogen ligands for supported coordinated platinum hydrosilylation catalysts SCO2, HAO2, PDCD1LG2 TDP2 4049/4885NSD2 1516/4885PAX8 2209/4885
US-20240334824-A1 Receptor material, synthesis method and use thereof TRPV4, TRPC6, RTN4 TDP2 4376/4885NSD2 3985/4885PAX8 1839/4885
US-12628491-B2 Organic-inorganic adhesion layer and its use in perovskite solar cells and modules EPCAM, CDH1, L1CAM TDP2 2532/4885NSD2 802/4885PAX8 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.