SCHEMBL3276015

SCHEMBL3276015

C=CS(=O)(=O)c1cc(S(=O)(=O)C=C)c(C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.38
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TP53 P04637 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
XBP1 P17861 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
MDM2 Q00987 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
BRD4 O60885 2/20 0.33
GAA P10253 1/20 0.32
GFER P55789 1/20 0.32
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22256260 0.82 MEN1 (0.53) ALDH1A1SMN1; SMN2TSHRHSD17B10TP53
SCHEMBL12810235 0.81 BRD4 (0.38) RAPGEF4ALDH1A1SMN1; SMN2TSHRHSD17B10
SCHEMBL11140861 0.79 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRLMNAMAPT
SCHEMBL7034798 0.79 ALDH1A1 (0.44) RAPGEF4ALDH1A1SMN1; SMN2HSD17B10LMNA
SCHEMBL11330232 0.76 EDNRB (0.42) ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL1
SCHEMBL11022458 0.76 L3MBTL1 (0.47) RAPGEF4ALDH1A1SMN1; SMN2TSHRHSD17B10
SCHEMBL11329213 0.76 CDK1 (0.46) ALDH1A1TP53LMNAMAPTGAA
SCHEMBL7718749 0.74 PKM (0.51) ALDH1A1TSHRHSD17B10LMNAMAPK1
SCHEMBL11338792 0.74 KMT2A (0.40) ALDH1A1SMN1; SMN2TSHRHSD17B10TP53
SCHEMBL24180006 0.74 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2TSHRHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6435678-B1 DEPOSITING PIGMENT BASED INK THEN HARDENER SOLUTION ON GLOSSY PAPER COATED WITH ACETOACETYLATED POLYVINYL ALCOHOL AND ADDITIONAL HARDENER; WET ADHESION; WATERFAST IMAGES EASTMAN KODAK COMPANY 2002-08-20 US claimed
US-6161929-A Inkjet images on PVA overcoated with hardener solution EASTMAN KODAK COMPANY (US) 2000-12-19 US claimed
US-6045219-A IMAGE DURABILITY EASTMAN KODAK COMPANY (US) 2000-04-04 US claimed
US-6031022-A STABILIZER IMPROVING THE RESISTANCE OF SOLID AREA PATCHES PRINTED ON COATED PAPERS AND FILMS TO BEING REMOVED BY WATER (WATERFASTNESS) EASTMAN KODAK COMPANY (US) 2000-02-29 US claimed
US-6020398-A ACETOCAETYLATED POLYVINYL ALCOHOL EASTMAN KODAK COMPANY (US) 2000-02-01 US claimed
CN-114502362-B Contact lenses with surfaces of different softness 爱尔康公司 2024-03-26 CN disclosed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN disclosed
EP-4314118-A1 POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX Alcon Inc. (CH) 2024-02-07 EP disclosed
CN-116888193-A Polysiloxane vinyl cross-linking agent with high refractive index 爱尔康公司 2023-10-13 CN disclosed
EP-4189469-A1 CONTACT LENSES WITH SOFTER LENS SURFACES Alcon Inc. (CH) 2023-06-07 EP disclosed
EP-4118134-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS Alcon Inc. (CH) 2023-01-18 EP disclosed
CN-115605529-A Photochromic polydiorganosiloxane ethylene crosslinkers 爱尔康公司(CH) 2023-01-13 CN disclosed
US-6020398-A ACETOCAETYLATED POLYVINYL ALCOHOL EASTMAN KODAK COMPANY (US) 2000-02-01 US disclosed
EP-0958933-A2 Pigmented ink jet inks and recording elements containing hardening agents EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed
EP-0958938-A1 Inkjet images printed on polyvinyl alcohol (PVA) and overcoated with a hardener solution EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed
EP-0958940-A1 Ink jet prints on gelatin-containing receiver, overcoated with hardeners EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed
EP-0958922-A2 Ink jet printing apparatus with print head for improved image durability EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed
EP-0958939-A1 Waterfast ink jet images treated with hardeners EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed
EP-0959113-A1 Pigmented ink jet inks for poly(vinylalcohol) receivers EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed
EP-0958921-A2 Printing apparatus with spray bar for improved durability EASTMAN KODAK COMPANY (US) 1999-11-24 EP disclosed