Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826531 | 0.85 | HDAC1 (0.45) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL9066111 | 0.85 | HDAC1 (0.45) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| Hydrochloric Acid SCHEMBL4954972 | 0.83 | HDAC1 (0.45) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL31060414 | 0.82 | HDAC1 (0.42) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL20840361 | 0.81 | KMT2A (0.51) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL12984801 | 0.81 | ALDH1A1 (0.49) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL3276911 | 0.80 | PDCD1 (0.48) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL7561830 | 0.79 | RAB9A (0.47) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL679864 | 0.79 | RAB9A (0.47) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL27623107 | 0.79 | HTT (0.45) | MAPK1NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687435-B2 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-1203083-A1 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | Diversa Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2000070056-A1 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | DIVERSA CORPORATION (US) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | PAH, TYR, BCAT2 | HDAC1 3630/4885HDAC3 3834/4885HDAC2 3654/4885 |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | PAH, PM20D2, FARSA | HDAC1 3163/4885HDAC3 3237/4885HDAC2 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.