Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537102 | 1.00 | SMPD2 (0.39) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL6550464 | 0.83 | ALDH1A1 (0.44) | NPSR1ALDH1A1KMT2ANPC1POLB | |
| Hydrochloric Acid SCHEMBL2313635 | 0.81 | ALDH1A1 (0.43) | NPSR1ALDH1A1KMT2ANPC1POLB | |
| SCHEMBL21776703 | 0.80 | NPSR1 (0.41) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL29442908 | 0.78 | NPSR1 (0.40) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL3276914 | 0.78 | ALDH1A1 (0.41) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL27779216 | 0.78 | SMPD2 (0.38) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL4564576 | 0.77 | ALDH1A1 (0.41) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10381409 | 0.77 | ALDH1A1 (0.41) | SMPD2NPSR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL3272814 | 0.77 | SMPD2 (0.42) | SMPD2NPSR1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687435-B2 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-1203083-A1 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | Diversa Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2000070056-A9 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | DIVERSA CORP (US) | 2001-11-29 | — | — | WO | disclosed |
| WO-2000070056-A1 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | DIVERSA CORPORATION (US) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | PAH, TYR, BCAT2 | SMPD2 1895/4885NPSR1 558/4885ALDH1A1 1239/4885 |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | PAH, PM20D2, FARSA | SMPD2 3494/4885NPSR1 1166/4885ALDH1A1 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.