Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797186 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL4456102 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL22588881 | 0.83 | ALPI (0.49) | ALDH1A1MAPTHSD17B10NPSR1ALPI | |
| SCHEMBL22588878 | 0.83 | ALPI (0.49) | ALDH1A1MAPTHSD17B10NPSR1ALPI | |
| SCHEMBL7405523 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL7405520 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL10861618 | 0.82 | MLYCD (0.45) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL27888110 | 0.82 | MLYCD (0.45) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL28294340 | 0.81 | KMT2A (0.40) | ALDH1A1LMNATP53SMN1; SMN2TSHR | |
| SCHEMBL28292699 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNATP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687435-B2 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142230-A1 | Benzoyl-substituted phenylalanineamides | PAH, TYR, BCAT2 | ALDH1A1 1239/4885LMNA 2263/4885TP53 3399/4885 |
| US-20070060480-A1 | Heteroaroyl-substituted phenylalanineamides | PAH, PM20D2, FARSA | ALDH1A1 2661/4885LMNA 3067/4885TP53 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.