Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516404 | 0.87 | CYP1A2 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL8033180 | 0.79 | TDP1 (0.45) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| SCHEMBL30170447 | 0.78 | CYP3A4 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL132132 | 0.78 | CYP3A4 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL29440576 | 0.78 | CYP3A4 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL7569519 | 0.78 | CYP3A4 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL133687 | 0.78 | CYP3A4 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL9327630 | 0.78 | CYP1A2 (0.44) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL2368837 | 0.78 | CYP1A2 (0.48) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL5440142 | 0.75 | NR4A1 (0.41) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560872-B | Heterocyclic imidazole compound and application thereof | 上海八亿时空先进材料有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114560872-A | Heterocyclic imidazole compound and application thereof | 上海八亿时空先进材料有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-7696349-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-1689760-B1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF SE (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-7442842-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20070073092-A1 | Method for asymmetric synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
| EP-1689760-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005051964-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073092-A1 | Method for asymmetric synthesis | COASY, PIN1, INF2 | CYP2A6 31/4885CYP1A2 127/4885ALDH1A1 2499/4885 |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | COASY, PIN1, INF2 | CYP2A6 31/4885CYP1A2 127/4885ALDH1A1 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.