SCHEMBL2516404

SCHEMBL2516404

ClP(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.48
CYP2A6 P11509 4/20 0.48
ALDH1A1 P00352 8/20 0.46
HSD17B10 Q99714 5/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
HPGD P15428 3/20 0.42
CYP3A4 P08684 2/20 0.42
KEAP1 Q14145 1/20 0.42
HPRT1 P00492 1/20 0.42
PAX8 Q06710 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
THRB P10828 1/20 0.39
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
NR4A1 P22736 1/20 0.37
NR4A2 P43354 1/20 0.37
NR4A3 Q92570 1/20 0.37
CA9 Q16790 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277146 0.87 CYP2A6 (0.41) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL2368837 0.85 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL517685 0.81 ALDH1A1 (0.53) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL9327630 0.81 CYP1A2 (0.44) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL29390280 0.79 ALDH1A1 (0.50) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL135987 0.79 ALDH1A1 (0.50) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL11861469 0.77 ALDH1A1 (0.48) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL15658735 0.77 ALDH1A1 (0.48) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL11826715 0.77 ALDH1A1 (0.48) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR
SCHEMBL11747361 0.75 ALDH1A1 (0.48) CYP1A2CYP2A6ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10700289-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-06-30 US disclosed
EP-3266779-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-06-03 EP disclosed
EP-1883688-B1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-11 EP disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-15 US disclosed
US-9461249-B2 Compounds for organic electronic devices MERCK PATENT GMBH (DE) 2016-10-04 US disclosed
US-9461249-B2 Compounds for organic electronic devices MERCK PATENT GMBH (DE) 2016-10-04 US disclosed
US-20150031896-A1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-01-29 US disclosed
US-20150031896-A1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-01-29 US disclosed
US-8852756-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-10-07 US disclosed
US-20040116726-A1 Process for preparing phosphites and transition metal complexes LANXESS DEUTSCHLAND GMBH (DE) 2004-06-17 US disclosed
US-6084133-A REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY KANKYO KAGAKU CENTER CO., LTD. (JP) 2000-07-04 US disclosed
EP-0115945-B1 SYNTHESIS OF HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLES CELANESE CORPORATION (US) 1988-11-30 EP disclosed
US-4680342-A Flame resistant alkenyl aromatic compounds and polymers containing chemically bonded phosphorus and blends with polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1987-07-14 US disclosed
US-4535144-A AMINOARYL ESTER REACTANT, TWO-STAGE MELT POLYMERIZATION CELANESE CORPORATION (US) 1985-08-13 US disclosed
US-4533725-A BY-PRODUCT INHIBITION; HEATING A FOAMED PREPOLYMER DELANESE CORPORATION (US) 1985-08-06 US disclosed
EP-0147724-A2 Flame resistant alkenyl aromatic compounds and polymers containing chemically bonded phosphorus and blends with polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1985-07-10 EP disclosed
EP-0115945-A2 Synthesis of high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-08-15 EP disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-3975447-A Preparation of aromatic phosphine oxides by reaction of diarylhalophosphine and benzylic halide E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180076395-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 CYP1A2 209/4885CYP2A6 355/4885ALDH1A1 750/4885
US-20150031896-A1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES TYR, TOE1, GPX1 CYP1A2 393/4885CYP2A6 1472/4885ALDH1A1 58/4885
US-10700289-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 CYP1A2 209/4885CYP2A6 355/4885ALDH1A1 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.