SCHEMBL3277301

SCHEMBL3277301

CCC1C=C(C(C)(C)C)C=C1[Zr](=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1)C1c2cc(C)c(C)cc2-c2cc(C)c(C)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOD2 Q9HC29 3/20 0.33
NOD1 Q9Y239 3/20 0.33
CES2 O00748 1/20 0.33
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
CNR2 P34972 2/20 0.31
GAA P10253 1/20 0.31
P2RX1 P51575 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
ADORA1 P30542 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277974 0.92 CES2 (0.33) NOD2NOD1CES2ALDH1A1POLB
SCHEMBL5153510 0.90 ACHE (0.33) NOD2NOD1CES2ALDH1A1POLB
SCHEMBL3277098 0.90
SCHEMBL3277383 0.86 NOD2 (0.30) NOD2NOD1
SCHEMBL3316323 0.85 NPSR1 (0.33) CES2ALDH1A1GAAMEN1CYP1A2
SCHEMBL3273560 0.81
SCHEMBL5157127 0.79 NOD2 (0.33) NOD2NOD1ALDH1A1POLBTAS1R3
SCHEMBL5272322 0.79
SCHEMBL3270908 0.79
SCHEMBL37570 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1803742-B1 PROCESS FOR PRODUCING PROPYLENE POLYMER MITSUI CHEMICALS INC (JP) 2010-06-23 EP disclosed