Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 6/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276721 | 0.84 | BTK (0.34) | NR4A2MAPK14ORAI1PTGESJAK2 | |
| SCHEMBL3277404 | 0.83 | PTGES (0.37) | ORAI1PTGESJAK2ALDH1A1 | |
| SCHEMBL13385463 | 0.82 | CCR1 (0.42) | NR4A2TYK2MAPK14LIMK1LIMK2 | |
| SCHEMBL13385490 | 0.78 | NR4A2 (0.43) | NR4A2PTGESFGFR1CCNT1MEN1 | |
| SCHEMBL13385493 | 0.77 | CYP1A1 (0.36) | NR4A2PTGES | |
| SCHEMBL13385499 | 0.76 | RAB9A (0.39) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13385494 | 0.75 | NR4A2 (0.37) | NR4A2TYK2MAPK14PTGESFGFR1 | |
| SCHEMBL3279738 | 0.72 | MAPK14 (0.43) | TYK2MAPK14LIMK1LIMK2MEN1 | |
| SCHEMBL13385480 | 0.71 | CCR1 (0.38) | MAPK14LIMK1LIMK2MEN1KMT2A | |
| SCHEMBL13385471 | 0.71 | IDH1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695728-B2 | 2-substituted pyridines, processes for their preparation and their use for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2010-04-13 | — | — | US | disclosed |
| EP-1761516-B1 | 2, 4, 5, 6-SUBSTITUTED PYRIMIDINES, METHOD FOR THE PRODUCTION AND USE THEREOF FOR COMBATING PARASITIC FUNGI | BASF AG (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-20070259919-A1 | 2-Substituted Pyridines, Processes for their Preparation and Their Use for Controlling Harmful Fungi | BASF AKIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259919-A1 | 2-Substituted Pyridines, Processes for their Preparation and Their Use for Controlling Harmful Fungi | CYP4X1, CYCS, CYP2S1 | NR4A2 779/4885TYK2 2668/4885MAPK14 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.