Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658057 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| SCHEMBL29658056 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| SCHEMBL1011611 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| SCHEMBL29658050 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| SCHEMBL1010378 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| SCHEMBL31069871 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| SCHEMBL29384464 | 1.00 | PRCP (0.61) | PRCPGAAHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL2262788 | 0.98 | PRCP (0.59) | PRCPGAAHTR2AHTR2CHTR2B | |
| Bromide SCHEMBL17674654 | 0.98 | PRCP (0.59) | PRCPGAAHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL19349458 | 0.98 | PRCP (0.59) | PRCPGAAHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425434-A1 | PREPARATION METHOD FOR 1,3-DISUBSTITUTED ALLENE COMPOUND AT ROOM TEMPERATURE BASED ON METAL CARBENE CATALYTIC SYSTEM | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2024-12-26 | — | — | US | claimed |
| CN-117427680-B | Preparation method of aromatic amine and unsaturated quinoline derivative | 烟台先进材料与绿色制造山东省实验室 | 2024-09-24 | — | — | CN | claimed |
| CN-114685369-B | Method for preparing 1-methyl-1, 2,3, 4-tetrahydroisoquinoline by utilizing ionic liquid | 河南省科学院高新技术研究中心 | 2024-02-02 | — | — | CN | claimed |
| CN-117427680-A | Preparation method of aromatic amine and unsaturated quinoline derivative | 烟台先进材料与绿色制造山东省实验室 | 2024-01-23 | — | — | CN | claimed |
| CN-115872825-A | Preparation method of 1,3-disubstituted allene compound based on gold carbene catalytic system at room temperature | 中国科学院上海有机化学研究所 | 2023-03-31 | — | — | CN | claimed |
| WO-2023046096-A1 | PREPARATION METHOD FOR 1,3-DISUBSTITUTED ALLENE COMPOUND AT ROOM TEMPERATURE BASED ON METAL CARBENE CATALYTIC SYSTEM | 中国科学院上海有机化学研究所 | 2023-03-30 | — | — | WO | claimed |
| CN-114685369-A | Method for preparing 1-methyl-1, 2,3, 4-tetrahydroisoquinoline by using ionic liquid | 河南省科学院高新技术研究中心 | 2022-07-01 | — | — | CN | claimed |
| CN-111621805-B | Method for preparing 3, 4-dihydroisoquinoline by electrocatalytic selective dehydrogenation | 天津大学 | 2022-02-18 | — | — | CN | claimed |
| CN-111943134-A | Room-temperature dehydrogenation reaction system of photocatalytic organic liquid hydrogen storage material and preparation method and application thereof | 中国科学院理化技术研究所 | 2020-11-17 | — | — | CN | claimed |
| CN-111621805-A | Method for preparing 3, 4-dihydroisoquinoline by electrocatalytic selective dehydrogenation | 天津大学 | 2020-09-04 | — | — | CN | claimed |
| EP-0946560-A1 | METHOD OF PREPARATION OF PHYSOSTIGMINE CARBAMATE DERIVATIVES FROM ESEROLINE ETHERS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-06 | — | — | EP | claimed |
| EP-0900214-A1 | PROCESS FOR PREPARATION OF PYRIMIDINE DERIVATIVES | Yuhan Corporation (KR) | 1999-03-10 | — | — | EP | claimed |
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | claimed |
| WO-1998027096-A1 | METHOD OF PREPARATION OF PHYSOSTIGMINE CARBAMATE DERIVATIVES FROM ESEROLINE ETHERS | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-25 | — | — | WO | claimed |
| WO-1997042186-A1 | PROCESS FOR PREPARATION OF PYRIMIDINE DERIVATIVES | YUHAN CORPORATION (KR) | 1997-11-13 | — | — | WO | claimed |
| US-5677457-A | REACTING ESERETHOLE WITH LITHIUM BROMIDE AND HYDROBROMIC ACID TO FORM ESEROLINE COMPOUND, TREATING WITH ISOCYANATE OR CARBONYLDIIMIDAZOLE | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-14 | — | — | US | claimed |
| US-5665880-A | Method of preparation of physostigmine carbamate derivatives from eseretholes | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-09 | — | — | US | claimed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | claimed |
| CN-1121072-A | Acetamides | MERCK PATENG GES MIT BESCHRANK (DE) | 1996-04-24 | — | — | CN | claimed |
| EP-0364996-A2 | Phosphono-hydroisoquinoline compounds useful in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1990-04-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425434-A1 | PREPARATION METHOD FOR 1,3-DISUBSTITUTED ALLENE COMPOUND AT ROOM TEMPERATURE BASED ON METAL CARBENE CATALYTIC SYSTEM | ADH1A, CYP51A1, ADH1C | PRCP 3169/4885GAA 3595/4885HTR2A 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.