⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709409 | 0.83 | — | — | |
| SCHEMBL10618897 | 0.78 | PTGS1 (0.55) | — | |
| SCHEMBL12294860 | 0.78 | — | — | |
| SCHEMBL6832737 | 0.78 | PTGS1 (0.55) | — | |
| Aspartic Acid SCHEMBL7706079 | 0.78 | PTGS1 (0.55) | — | |
| Aspartic Acid SCHEMBL1526976 | 0.77 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL11065189 | 0.77 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL3230 | 0.77 | — | — | |
| Aspartic Acid SCHEMBL11065185 | 0.77 | GRIK1 (0.56) | — | |
| Aspartic Acid SCHEMBL3231 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | claimed |
| US-7018989-B2 | Chemical compounds | UNIVERSITY COLLEGE CARDIFF CONSULTANTS, LTD (GB) | 2006-03-28 | — | — | US | claimed |
| US-6455513-B1 | ARYL SUBSTITUTED PHOSPHORYL DERIVATIVES; VIRICIDES AGAINST HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRUSES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2002-09-24 | — | — | US | claimed |
| US-5326867-A | Antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-05 | — | — | US | claimed |
| EP-0580480-A1 | Pradimic acids, amides, and novel pradimicin derivatives | Bristol-Myers Squibb Company (US) | 1994-01-26 | — | — | EP | claimed |
| US-7700087-B2 | Compounds and methods to inhibit or augment an inflammatory response | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | disclosed |
| EP-1012187-B1 | CHEMOKINE PEPTIDES, VARIANTS, DERIVATIVES AND ANALOGS. THEIR USE IN METHODS TO INHIBIT OR AUGMENT AN INFLAMMATORY RESPONSE | CAMBRIDGE ENTPR LTD (GB) | 2009-08-26 | — | — | EP | disclosed |
| EP-2069299-A2 | ANESTHETIC COMPOUNDS | Pharmacofore, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008011539-A2 | ANESTHETIC COMPOUNDS | PHARMACOFORE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| US-7067117-B1 | Compounds and methods to inhibit or augment an inflammatory response | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES, LTD. (GB) | 2006-06-27 | — | — | US | disclosed |
| US-20060073114-A1 | Compounds and methods to inhibit or augment an inflammatory response | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD. | 2006-04-06 | — | — | US | disclosed |
| US-6455513-B1 | ARYL SUBSTITUTED PHOSPHORYL DERIVATIVES; VIRICIDES AGAINST HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRUSES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2002-09-24 | — | — | US | disclosed |
| EP-1012187-A2 | CHEMOKINE PEPTIDES, VARIANTS, DERIVATIVES AND ANALOGS. THEIR USE IN METHODS TO INHIBIT OR AUGMENT AN INFLAMMATORY RESPONSE | NEORX CORPORATION (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999012968-A2 | CHEMOKINE PEPTIDES, VARIANTS, DERIVATIVES AND ANALOGS, THEIR USE IN METHODS TO INHIBIT OR AUGMENT AN INFLAMMATORY RESPONSE | NEORX CORPORATION (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5608044-A | ANTIBIOTIC INTERMEDIATES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5414073-A | Treatment with dimethylphosphoryl azide and hydrolysis | BRISTOL-MYERS SQUIBB (US) | 1995-05-09 | — | — | US | disclosed |
| US-5326867-A | Antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0580480-A1 | Pradimic acids, amides, and novel pradimicin derivatives | Bristol-Myers Squibb Company (US) | 1994-01-26 | — | — | EP | disclosed |